The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

Blood viscosity is an important determinant of local flow characteristics, which exhibits shear
thinning behavior: it decreases exponentially with increasing shear rates. Both hematocrit …

Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

Background: Current paradigms suggest that nitric oxide (NO) produced by endothelial cells
(ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary …

Significance: Recent clinical evidence identified anemia to be correlated with severe
complications of cardiovascular disease (CVD) such as bleeding, thromboembolic events …

Sepsis is aggravated by an inappropriate immune response to invading microorganisms,
which occasionally leads to multiple organ failure. Several lines of evidence suggest that the …

Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …

During exercise the cardiovascular system has to warrant substrate supply to working
muscle. The main function of red blood cells in exercise is the transport of O2 from the lungs …