Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications
Introduction Biological fluids are routine samples for diagnostic testing and monitoring.
Blood samples are typically measured because of their moderate invasive collection and …
Blood samples are typically measured because of their moderate invasive collection and …
Cerebrospinal fluid: a target of some fungi and an overview
Meningitis is a potentially life-threatening infection characterised by the inflammation of the
leptomeningeal membranes. The estimated annual prevalence of 8.7 million cases globally …
leptomeningeal membranes. The estimated annual prevalence of 8.7 million cases globally …
Multienzyme deep learning models improve peptide de novo sequencing by mass spectrometry proteomics
Generating and analyzing overlap** peptides through multienzymatic digestion is an
efficient procedure for de novo protein using from bottom-up mass spectrometry (MS) …
efficient procedure for de novo protein using from bottom-up mass spectrometry (MS) …
[HTML][HTML] The worldwide prevalence of herpes simplex virus Encephalitis and Meningitis: a systematic review and meta-analysis
Given the relatively high frequency of central nervous system infections and considerable
mortality and morbidity reported to be caused by herpes simplex viruses among the other …
mortality and morbidity reported to be caused by herpes simplex viruses among the other …
Metagenomic next-generation sequencing and proteomics analysis in pediatric viral encephalitis and meningitis
YL Wang, XT Guo, MY Zhu, YC Mao, XB Xu… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Early and accurate identification of pathogens is essential for improved
outcomes in patients with viral encephalitis (VE) and/or viral meningitis (VM). Methods In our …
outcomes in patients with viral encephalitis (VE) and/or viral meningitis (VM). Methods In our …
Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection
Japanese encephalitis virus is a leading cause of neurological infection in the Asia-Pacific
region with no means of detection in more remote areas. We aimed to test the hypothesis of …
region with no means of detection in more remote areas. We aimed to test the hypothesis of …
[HTML][HTML] Application of metabolomics in diagnostics and differentiation of meningitis: A narrative review with a critical approach to the literature
A Kozioł, M Pupek, Ł Lewandowski - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Due to its high mortality rate associated with various life-threatening sequelae, meningitis
poses a vital problem in contemporary medicine. Numerous algorithms, many of which were …
poses a vital problem in contemporary medicine. Numerous algorithms, many of which were …
Metabolomic characterization of cerebrospinal fluid from intracranial bacterial infection pediatric patients: a pilot study
Y Wang, Y Liu, R Chen, L Qiao - Molecules, 2021 - mdpi.com
Intracranial bacterial infection remains a major cause of morbidity and mortality in
neurosurgical cases. Metabolomic profiling of cerebrospinal fluid (CSF) holds great promise …
neurosurgical cases. Metabolomic profiling of cerebrospinal fluid (CSF) holds great promise …
Temporal pathway analysis of cerebrospinal fluid proteome in herpes simplex encephalitis
Objectives We examined the temporal changes of the CSF proteome in patients with herpes
simplex encephalitis (HSE) during the course of the disease, in relation to anti-N-methyl-D …
simplex encephalitis (HSE) during the course of the disease, in relation to anti-N-methyl-D …
Proteomic approaches to unravel mechanisms of antibiotic resistance and immune evasion of bacterial pathogens
The profound effects of and distress caused by the global COVID-19 pandemic highlighted
what has been known in the health sciences a long time ago: that bacteria, fungi, viruses …
what has been known in the health sciences a long time ago: that bacteria, fungi, viruses …