Strengths and limitations of in silico tools to assess physicochemical properties, bioactivity, and bioavailability of food-derived peptides

F Rivero-Pino, MC Millan-Linares… - Trends in Food Science …, 2023 - Elsevier
Background Bioactive peptides obtained from different food sources have been proved to
exert several bioactivities, such as antioxidant, antihypertensive, antimicrobial, or anti …

A comprehensive review of patented antimicrobial peptides from amphibian anurans

FA García, TF Fuentes, IP Alonso… - Journal of Natural …, 2024 - ACS Publications
Since the 1980s, studies of antimicrobial peptides (AMPs) derived from anuran skin
secretions have unveiled remarkable structural diversity and a wide range of activities. This …

Membrane-active peptides and their potential biomedical application

A Gostaviceanu, S Gavrilaş, L Copolovici… - Pharmaceutics, 2023 - mdpi.com
Membrane-active peptides (MAPs) possess unique properties that make them valuable tools
for studying membrane structure and function and promising candidates for therapeutic …

Purification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae)

JM Conlon, L Guilhaudis, S Attoub, L Coquet… - Antibiotics, 2023 - mdpi.com
Frogs from the extensive amphibian family Hylidae are a rich source of peptides with
therapeutic potential. Peptidomic analysis of norepinephrine-stimulated skin secretions from …

Influence of Fatty Acid Modification on the Anticancer Activity of the Antimicrobial Peptide Figainin 1

Z Han, D Feng, W Wang, Y Wang, M Cheng, H Yang… - ACS …, 2023 - ACS Publications
Antimicrobial peptides derived from the skin secretions of amphibians have made important
progress in tumor therapy due to their unique mechanism of destroying cell membranes …

The significance of hypervariability and conserved motifs in antimicrobial peptides from tree frogs

AE Brunetti, CA Fuzo, S Aguilar… - Journal of Natural …, 2023 - ACS Publications
Amphibians' skin is a rich source of natural antimicrobial peptides (AMPs). These AMPs
exhibit marked inter-and intraspecific sequence divergence linked to the arms race between …

First Bioprospecting Study of Skin Host-Defense Peptides in Odontophrynus americanus

NL Cancelarich, M Arrulo, ST Gugliotti… - Journal of Natural …, 2024 - ACS Publications
The adaptation of amphibians to diverse environments is closely related to the
characteristics of their skin. The complex glandular system of frog skin plays a pivotal role in …

Unraveling the Effects of Cationic Peptides on Vesicle Structures: Insights into Peptide–Membrane Interactions

R Alfred, G Bryant, JP Mata, M Bhave… - ACS Applied Bio …, 2023 - ACS Publications
Antimicrobial resistance is a pressing global health issue, with millions of lives at risk by
2050, necessitating the development of alternatives with broad-spectrum activity against …

[HTML][HTML] Multifunctional host-defense peptides isolated from skin secretions of the banana tree dwelling frog Boana platanera (Hylidae; Hylinae)

JM Conlon, A Sridhar, D Khan, TS Cunning… - Biochimie, 2024 - Elsevier
Five host-defense peptides (figainin 2PL, hylin PL, raniseptin PL, plasticin PL, and peptide
YL) were isolated from norepinephrine-stimulated skin secretions of the banana tree …

[PDF][PDF] Membrane-Active Peptides and Their Potential Biomedical Application. Pharmaceutics 2023, 15, 2091

A Gostaviceanu, S Gavrilas, L Copolovici… - 2023 - academia.edu
Membrane-active peptides (MAPs) possess unique properties that make them valuable tools
for studying membrane structure and function and promising candidates for therapeutic …