Traumatic brain injury: Mechanisms, manifestations, and visual sequelae
SH Rauchman, A Zubair, B Jacob… - Frontiers in …, 2023 - frontiersin.org
Traumatic brain injury (TBI) results when external physical forces impact the head with
sufficient intensity to cause damage to the brain. TBI can be mild, moderate, or severe and …
sufficient intensity to cause damage to the brain. TBI can be mild, moderate, or severe and …
Insights into epileptogenesis from post-traumatic epilepsy
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …
[HTML][HTML] Mouse model of focal cortical dysplasia type II generates a wide spectrum of high-frequency activities
J Chvojka, N Prochazkova, M Rehorova… - Neurobiology of …, 2024 - Elsevier
High-frequency oscillations (HFOs) represent an electrographic biomarker of endogenous
epileptogenicity and seizure-generating tissue that proved clinically useful in presurgical …
epileptogenicity and seizure-generating tissue that proved clinically useful in presurgical …
[HTML][HTML] Chloride ion dysregulation in epileptogenic neuronal networks
SA Weiss - Neurobiology of Disease, 2023 - Elsevier
GABA is the major inhibitory neurotransmitter in the mature CNS. When GABA A receptors
are activated the membrane potential is driven towards hyperpolarization due to chloride …
are activated the membrane potential is driven towards hyperpolarization due to chloride …
Pathological neurons generate ripples at the UP‐DOWN transition disrupting information transfer
Objective To confirm and investigate why pathological high‐frequency oscillations (pHFOs),
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …
Pathological and physiological high-frequency oscillations on electroencephalography in patients with epilepsy
High-frequency oscillations (HFOs) encompass ripples (80 Hz–200 Hz) and fast ripples (200
Hz–600 Hz), serving as a promising biomarker for localizing the epileptogenic zone in …
Hz–600 Hz), serving as a promising biomarker for localizing the epileptogenic zone in …
Graph theoretical measures of fast ripple networks improve the accuracy of post-operative seizure outcome prediction
Fast ripples (FR) are a biomarker of epileptogenic brain, but when larger portions of FR
generating regions are resected seizure freedom is not always achieved. To evaluate and …
generating regions are resected seizure freedom is not always achieved. To evaluate and …
Neurophysiology, Neuropsychology, and Epilepsy, in 2022: Hills We Have Climbed and Hills Ahead. Neurophysiology in epilepsy
Since the discovery of the human electroencephalogram (EEG), neurophysiology
techniques have become indispensable tools in our armamentarium to localize epileptic …
techniques have become indispensable tools in our armamentarium to localize epileptic …
Electrically-evoked oscillating calcium transients in mono-and co-cultures of iPSC glia and sensory neurons
J Lawson, E LaVancher, M DeAlmeida… - Frontiers in Cellular …, 2023 - frontiersin.org
Activated glia are known to exhibit either neuroprotective or neurodegenerative effects,
depending on their phenotype, while participating in chronic pain regulation. Until recently, it …
depending on their phenotype, while participating in chronic pain regulation. Until recently, it …
Preventive effects of transcranial photobiomodulation on epileptogenesis in a kainic acid-induced rat epilepsy model
Objective Temporal lobe epilepsy affects nearly 50 million people worldwide and is a major
burden to families and society. A significant portion of patients are living in develo** …
burden to families and society. A significant portion of patients are living in develo** …