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[HTML][HTML] Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …
Dendrimers for drug delivery: An overview of its classes, synthesis, and applications
RJ Sarode, HS Mahajan - Journal of Drug Delivery Science and …, 2024 - Elsevier
The dendrimers in pharmaceuticals received much consideration from the scientific fraternity
due to their unique and versatile characteristics. Primarily, it includes monodispersity, three …
due to their unique and versatile characteristics. Primarily, it includes monodispersity, three …
Dendrimers and hyperbranched structures for biomedical applications
E Pedziwiatr-Werbicka, K Milowska, V Dzmitruk… - European Polymer …, 2019 - Elsevier
The use of nanotechnology in biology and medicine has been marked by rapid progress of
these industries due to the emergence of new devices, supramolecular systems, structures …
these industries due to the emergence of new devices, supramolecular systems, structures …
Carbosilane dendrimers: Drug and gene delivery applications
Carbosilane dendrimers are a particular type of dendrimer structure that has been used as
delivery vehicles for drugs and nucleic acids. They have a defined structure according to …
delivery vehicles for drugs and nucleic acids. They have a defined structure according to …
Dendrimers show promise for siRNA and microRNA therapeutics
The lack of an appropriate intracellular delivery system for therapeutic nucleic acids (TNAs)
is a major problem in molecular biology, biotechnology, and medicine. A relatively new class …
is a major problem in molecular biology, biotechnology, and medicine. A relatively new class …
Poly (lysine) dendrimers form complexes with siRNA and provide its efficient uptake by myeloid cells: model studies for therapeutic nucleic acid delivery
M Gorzkiewicz, O Kopeć, A Janaszewska… - International Journal of …, 2020 - mdpi.com
The disruption of the cellular pathways of protein biosynthesis through the mechanism of
RNA interference has been recognized as a tool of great diagnostic and therapeutic …
RNA interference has been recognized as a tool of great diagnostic and therapeutic …
Dendrimers as carriers for siRNA delivery and gene silencing: a review
J Wu, W Huang, Z He - The Scientific World Journal, 2013 - Wiley Online Library
RNA interference (RNAi) was first literaturally reported in 1998 and has become rapidly a
promising tool for therapeutic applications in gene therapy. In a typical RNAi process, small …
promising tool for therapeutic applications in gene therapy. In a typical RNAi process, small …
Nanoparticles in combating cancer: Opportunities and limitations: A brief review
E Pedziwiatr-Werbicka, K Horodecka… - Current Medicinal …, 2021 - ingentaconnect.com
Nanomedicine is a good alternative to traditional methods of cancer treatment but does not
solve all the limitations of oncology. Nanoparticles used in anticancer therapy can work as …
solve all the limitations of oncology. Nanoparticles used in anticancer therapy can work as …
Biological properties of new viologen-phosphorus dendrimers
Some biological properties of eight dendrimers incorporating both phosphorus linkages and
viologen units within their cascade structure or at the periphery were investigated for the first …
viologen units within their cascade structure or at the periphery were investigated for the first …
Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (B). Efficiency of pharmacological action
This paper examines a perspective to use newly engineered nanomaterials as effective and
safe carriers for gene therapy of cancer. Three different groups of cationic dendrimers …
safe carriers for gene therapy of cancer. Three different groups of cationic dendrimers …