Immune responses to stroke: mechanisms, modulation, and therapeutic potential
Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Salt Reduction to Prevent Hypertension and Cardiovascular Disease: JACC State-of-the-Art Review
There is strong evidence for a causal relationship between salt intake and blood pressure.
Randomized trials demonstrate that salt reduction lowers blood pressure in both individuals …
Randomized trials demonstrate that salt reduction lowers blood pressure in both individuals …
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease …
X Wang, G Sun, T Feng, J Zhang, X Huang, T Wang… - Cell research, 2019 - nature.com
Recently, increasing evidence has suggested the association between gut dysbiosis and
Alzheimer's disease (AD) progression, yet the role of gut microbiota in AD pathogenesis …
Alzheimer's disease (AD) progression, yet the role of gut microbiota in AD pathogenesis …
Vascular Cognitive Impairment and Dementia: JACC Scientific Expert Panel
Cognitive impairment associated with aging has emerged as one of the major public health
challenges of our time. Although Alzheimer's disease is the leading cause of clinically …
challenges of our time. Although Alzheimer's disease is the leading cause of clinically …
The IL-17 family of cytokines in health and disease
The interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines, IL-17A
through IL-17F. IL-17A, the prototypical member of this family, just passed the 25 th …
through IL-17F. IL-17A, the prototypical member of this family, just passed the 25 th …
Molecular biomarkers for vascular cognitive impairment and dementia
As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …
Meningeal interleukin-17-producing T cells mediate cognitive impairment in a mouse model of salt-sensitive hypertension
Hypertension (HTN), a disease afflicting over one billion individuals worldwide, is a leading
cause of cognitive impairment, the mechanisms of which remain poorly understood. In the …
cause of cognitive impairment, the mechanisms of which remain poorly understood. In the …
Hypertension, neurovascular dysfunction, and cognitive impairment
Hypertension affects a significant proportion of the adult and aging population and
represents an important risk factor for vascular cognitive impairment and late-life dementia …
represents an important risk factor for vascular cognitive impairment and late-life dementia …
Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of …
Vascular contributions to cognitive impairment and dementia (VCID) are characterized by
the aging neurovascular unit being confronted with and failing to cope with biological insults …
the aging neurovascular unit being confronted with and failing to cope with biological insults …
Peripheral nerves directly mediate the transneuronal translocation of silver nanomaterials from the gut to central nervous system
The blood circulation is considered the only way for the orally administered nanoparticles to
enter the central nervous systems (CNS), whereas non-blood route-mediated nanoparticle …
enter the central nervous systems (CNS), whereas non-blood route-mediated nanoparticle …