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Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
Aggregation-induced emission: together we shine, united we soar!
Light is of essential importance to the universe and humankind. Light has been, and
continues to be, one of the most fundamental and indispensable elements to life and society …
continues to be, one of the most fundamental and indispensable elements to life and society …
Fluorescent probes for sensing and imaging within specific cellular organelles
H Zhu, J Fan, J Du, X Peng - Accounts of chemical research, 2016 - ACS Publications
Conspectus Fluorescent probes have become powerful tools in biosensing and bioimaging
because of their high sensitivity, specificity, fast response, and technical simplicity. In the last …
because of their high sensitivity, specificity, fast response, and technical simplicity. In the last …
Discerning the chemistry in individual organelles with small‐molecule fluorescent probes
Principle has it that even the most advanced super‐resolution microscope would be futile in
providing biological insight into subcellular matrices without well‐designed fluorescent …
providing biological insight into subcellular matrices without well‐designed fluorescent …
Synthesis and application of coumarin fluorescence probes
X Sun, T Liu, J Sun, X Wang - RSC advances, 2020 - pubs.rsc.org
In recent years, the research on fluorescent probes has developed rapidly. Coumarin
fluorescent probes have also been one of the hot topics in recent years. For the synthesis …
fluorescent probes have also been one of the hot topics in recent years. For the synthesis …
BODIPY-based probes for the fluorescence imaging of biomolecules in living cells
Fluorescence imaging techniques have been widely used to visualize biological molecules
and phenomena. In particular, several studies on the development of small-molecule …
and phenomena. In particular, several studies on the development of small-molecule …
De novo design of chemical stability near-infrared molecular probes for high-fidelity hepatotoxicity evaluation in vivo
D Cheng, J Peng, Y Lv, D Su, D Liu… - Journal of the …, 2019 - ACS Publications
Near-infrared (NIR) fluorescence imaging technique is garnering increasing research
attention due to various advantages. However, most NIR fluorescent probes still suffer from a …
attention due to various advantages. However, most NIR fluorescent probes still suffer from a …
Reactive oxygen species (ROS)-responsive prodrugs, probes, and theranostic prodrugs: applications in the ROS-related diseases
P Wang, Q Gong, J Hu, X Li… - Journal of medicinal …, 2020 - ACS Publications
Elevated levels of reactive oxygen species (ROS) have commonly been implicated in a
variety of diseases, including cancer, inflammation, and neurodegenerative diseases. In …
variety of diseases, including cancer, inflammation, and neurodegenerative diseases. In …
Reaction-based BODIPY probes for selective bio-imaging
Complex intracellular environment of cells, which involves interaction of a large variety of bio-
molecules, is a dynamic medium with full of important information that can be recovered as …
molecules, is a dynamic medium with full of important information that can be recovered as …
Overview of reactive oxygen species
The increasing concentration of molecular oxygen (O2) in the atmosphere roughly 2.5 billion
years ago, 1, 2 due to oxygenic photosynthesis by cyanobacteria, allowed for the evolution …
years ago, 1, 2 due to oxygenic photosynthesis by cyanobacteria, allowed for the evolution …