Structure, function, and pharmacology of glutamate receptor ion channels
Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
Current trends and new challenges in marine phycotoxins
Marine phycotoxins are a multiplicity of bioactive compounds which are produced by
microalgae and bioaccumulate in the marine food web. Phycotoxins affect the ecosystem …
microalgae and bioaccumulate in the marine food web. Phycotoxins affect the ecosystem …
Architecture and function of NMDA receptors: an evolutionary perspective
D Stroebel, P Paoletti - The Journal of Physiology, 2021 - Wiley Online Library
Ionotropic glutamate receptors (iGluRs) are a major class of ligand‐gated ion channels that
are widespread in the living kingdom. Their critical role in excitatory neurotransmission and …
are widespread in the living kingdom. Their critical role in excitatory neurotransmission and …
Kainate receptor antagonists: recent advances and therapeutic perspective
P Chałupnik, E Szymańska - International Journal of Molecular Sciences, 2023 - mdpi.com
Since the 1990s, ionotropic glutamate receptors have served as an outstanding target for
drug discovery research aimed at the discovery of new neurotherapeutic agents. With the …
drug discovery research aimed at the discovery of new neurotherapeutic agents. With the …
Targeting ionotropic glutamate receptors in the treatment of epilepsy
R Celli, F Fornai - Current Neuropharmacology, 2021 - ingentaconnect.com
Background: A dysfunction in glutamate neurotransmission is critical for seizure. Glutamate
is the major excitatory drive in the cerebral cortex, where seizures occur. Glutamate acts via …
is the major excitatory drive in the cerebral cortex, where seizures occur. Glutamate acts via …
Structure of the Arabidopsis glutamate receptor-like channel GLR3. 2 ligand-binding domain
SP Gangwar, MN Green, E Michard, AA Simon… - Structure, 2021 - cell.com
Glutamate receptor-like channels (GLRs) play important roles in numerous plant
physiological processes. GLRs are homologous to ionotropic glutamate receptors (iGluRs) …
physiological processes. GLRs are homologous to ionotropic glutamate receptors (iGluRs) …
Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
Kainate receptors (KARs) are L-glutamate-gated ion channels that regulate synaptic
transmission and modulate neuronal circuits. KARs have strict assembly rules and primarily …
transmission and modulate neuronal circuits. KARs have strict assembly rules and primarily …
[PDF][PDF] Pathophysiology of Perinatal Hypoxic-Ischemic Encephalopathy--Biomarkers, Animal Models and Treatment Perspectives.
V Riljak, J Kraf, A Daryanani, P Jiruška… - Physiological …, 2016 - biomed.cas.cz
Hypoxic-ischemic encephalopathy (HIE) is one of the leading pediatric neurological
conditions causing long-term disabilities and socio-economical burdens. Nearly 20-50% of …
conditions causing long-term disabilities and socio-economical burdens. Nearly 20-50% of …
Exciting times: new advances towards understanding the regulation and roles of kainate receptors
Kainate receptors (KARs) are glutamate-gated ion channels that play fundamental roles in
regulating neuronal excitability and network function in the brain. After being cloned in the …
regulating neuronal excitability and network function in the brain. After being cloned in the …
Structure, function, and regulation of the kainate receptor
Neural communication and modulation are complex processes. Ionotropic glutamate
receptors (iGluRs) significantly contribute to mediating the fast-excitatory branch of …
receptors (iGluRs) significantly contribute to mediating the fast-excitatory branch of …