Background: Whether circulating sex hormones modulate mortality and cardiovascular
disease (CVD) risk in aging men is controversial. Purpose: To clarify associations of sex …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Context The benefits and harms of varicocele treatment versus observation in adult infertile
males are still controversial. Objective To systematically pool the evidence on outcomes of …

Aging of humans is associated with functional alterations at all levels of the reproductive axis
and affects both steroidogenic and spermatogenic compartments. Unlike female …

Advanced paternal age is associated with increased sperm reactive oxygen species (ROS)
and decreased fertilization and pregnancy rates. Sperm washing during infertility treatment …

Background Women with menopausal transition (MT) have an elevated risk of experiencing
common mental health diagnoses (CMHD: depression or anxiety). There is no recent data …

The increase in life expectancy is accompanied with an increased consultation of age-
related pathologies including endocrine disorders. Two main areas are focusing the …

Polybrominated diphenyl ethers (PBDEs) are widely used brominated flame retardants, they
are easily released into environment and causing adverse effects to the ecosystem and …

In older men, an age-related decline in testosterone is closely associated with various
adverse health outcomes. With the progression of aging, hyperactivation of the local renin …

Reproductive aging, spanning an age-related functional decline in the female and male
reproductive systems, compromises fertility and leads to a range of health complications. In …