A comprehensive review of machine learning algorithms and their application in geriatric medicine: present and future

RJ Woodman, AA Mangoni - Aging Clinical and Experimental Research, 2023 - Springer
The increasing access to health data worldwide is driving a resurgence in machine learning
research, including data-hungry deep learning algorithms. More computationally efficient …

Biomedical big data technologies, applications, and challenges for precision medicine: a review

X Yang, K Huang, D Yang, W Zhao… - Global Challenges, 2024 - Wiley Online Library
The explosive growth of biomedical Big Data presents both significant opportunities and
challenges in the realm of knowledge discovery and translational applications within …

Enrichr-KG: bridging enrichment analysis across multiple libraries

JE Evangelista, Z **e, GB Marino… - Nucleic acids …, 2023 - academic.oup.com
Gene and protein set enrichment analysis is a critical step in the analysis of data collected
from omics experiments. Enrichr is a popular gene set enrichment analysis web-server …

Leveraging electronic health records and knowledge networks for Alzheimer's disease prediction and sex-specific biological insights

AS Tang, KP Rankin, G Cerono, S Miramontes, H Mills… - Nature Aging, 2024 - nature.com
Identification of Alzheimer's disease (AD) onset risk can facilitate interventions before
irreversible disease progression. We demonstrate that electronic health records from the …

Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction

K Siew, KA Nestler, C Nelson, V D'Ambrosio… - Nature …, 2024 - nature.com
Abstract Missions into Deep Space are planned this decade. Yet the health consequences
of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions …

Emerging tools and best practices for studying gut microbial community metabolism

C Noecker, PJ Turnbaugh - Nature Metabolism, 2024 - nature.com
The human gut microbiome vastly extends the set of metabolic reactions catalysed by our
own cells, with far-reaching consequences for host health and disease. However, our …

Biomedical knowledge graph-optimized prompt generation for large language models

K Soman, PW Rose, JH Morris, RE Akbas… - …, 2024 - academic.oup.com
Abstract Motivation Large language models (LLMs) are being adopted at an unprecedented
rate, yet still face challenges in knowledge-intensive domains such as biomedicine …

NASA open science data repository: open science for life in space

SG Gebre, RT Scott, AM Saravia-Butler… - Nucleic Acids …, 2025 - academic.oup.com
Abstract Space biology and health data are critical for the success of deep space missions
and sustainable human presence off-world. At the core of effectively managing biomedical …

Identifying therapeutic candidates for endometriosis through a transcriptomics-based drug repositioning approach

TT Oskotsky, A Bhoja, D Bunis, BL Le, AS Tang, I Kosti… - Iscience, 2024 - cell.com
Existing medical treatments for endometriosis-related pain are often ineffective,
underscoring the need for new therapeutic strategies. In this study, we applied a …

Inspiration4 data access through the NASA Open Science Data Repository

LM Sanders, KA Grigorev, RT Scott… - npj …, 2024 - nature.com
The increasing accessibility of commercial and private space travel necessitates a profound
understanding of its impact on human health. The NASA Open Science Data Repository …