NO donors as the wonder molecules with therapeutic potential: Recent trends and future perspectives
Nitric oxide (NO), an endogenous, free radical, highly unstable, diatomic gaseous molecule,
plays crucial roles in several physiological and pathological processes. It has attracted …
plays crucial roles in several physiological and pathological processes. It has attracted …
Nitric oxide as a central molecule in hypertension: Focus on the vasorelaxant activity of new nitric oxide donors
GM da Silva, MC da Silva, DVG Nascimento… - Biology, 2021 - mdpi.com
Simple Summary Nitric oxide is an important molecule that performs a variety of functions in
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …
State-of-the-Art and Perspectives for Nanomaterials Combined with Nitric Oxide Donors: From Biomedical to Agricultural Applications
The free radical nitric oxide (NO) is a signaling molecule that controls several important
physiological and pathophysiological processes in mammals and in plants. In humans, the …
physiological and pathophysiological processes in mammals and in plants. In humans, the …
Nitric oxide releasing nanomaterials for cardiovascular applications
A central paradigm of cardiovascular homeostasis is that impaired nitric oxide (NO)
bioavailability results in a wide array of cardiovascular dysfunction including incompetent …
bioavailability results in a wide array of cardiovascular dysfunction including incompetent …
Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue
LS Hoffmann, J Etzrodt, L Willkomm, A Sanyal… - Nature …, 2015 - nature.com
Obesity is characterized by a positive energy balance and expansion of white adipose tissue
(WAT). In contrast, brown adipose tissue (BAT) combusts energy to produce heat. Here we …
(WAT). In contrast, brown adipose tissue (BAT) combusts energy to produce heat. Here we …
NO and HNO donors, nitrones, and nitroxides: Past, present, and future
The biological effects attributed to nitric oxide (• NO) and nitroxyl (HNO) have been
extensively studied, propelling their array of putative clinical applications beyond …
extensively studied, propelling their array of putative clinical applications beyond …
Adverse events associated with coprescription of phosphodiesterase type 5 inhibitors and oral organic nitrates in male patients with ischemic heart disease: a case …
Background: Concomitant use of oral organic nitrates (nitrates) and phosphodiesterase type
5 (PDE5) inhibitors is contraindicated. Objective: To measure temporal trends in the …
5 (PDE5) inhibitors is contraindicated. Objective: To measure temporal trends in the …
Advances in nitric oxide regulators for the treatment of ischemic stroke
J Wu, J Jia, D Ji, W Jiao, Z Huang, Y Zhang - European Journal of …, 2023 - Elsevier
Ischemic stroke (IS) is a life-threatening disease worldwide. Nitric oxide (NO) derived from l-
arginine catalyzed by NO synthase (NOS) is closely associated with IS. Three isomers of …
arginine catalyzed by NO synthase (NOS) is closely associated with IS. Three isomers of …
Simple and versatile nitrooxylation: Noncyclic hypervalent iodine nitrooxylating reagent
X Cheng, Q Yin, YX Jiang, LF Jiang… - Angewandte Chemie …, 2023 - Wiley Online Library
Organic nitrates are broadly applied as pharmaceuticals (acting as efficient nitric oxide
donor), energetic materials, building blocks in organic synthesis, etc. However, practical and …
donor), energetic materials, building blocks in organic synthesis, etc. However, practical and …
Pharmacological applications of nitric oxide-releasing biomaterials in human skin
Nitric oxide (NO) is an important endogenous molecule that plays several roles in biological
systems. NO is synthesized in human skin by three isoforms of nitric oxide synthase (NOS) …
systems. NO is synthesized in human skin by three isoforms of nitric oxide synthase (NOS) …