Antioxidant and anti-inflammatory potential of polyphenols contained in mediterranean diet in obesity: Molecular mechanisms

A Nani, B Murtaza, A Sayed Khan, NA Khan, A Hichami - Molecules, 2021 - mdpi.com
Nutrition transition can be defined as shifts in food habits, and it is characterized by high-fat
(chiefly saturated animal fat), hypercaloric and salty food consumption at the expense of …

Epigenetic signatures underlying inflammation: An interplay of nutrition, physical activity, metabolic diseases, and environmental factors for personalized nutrition

O Ramos-Lopez, FI Milagro, JI Riezu-Boj… - Inflammation …, 2021 - Springer
Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …

Insight into polyphenol and gut microbiota crosstalk: are their metabolites the key to understand protective effects against metabolic disorders?

M Koudoufio, Y Desjardins, F Feldman, S Spahis… - Antioxidants, 2020 - mdpi.com
Lifestyle factors, especially diet and nutrition, are currently regarded as essential avenues to
decrease modern-day cardiometabolic disorders (CMD), including obesity, metabolic …

Sarcopenia, a condition shared by various diseases: can we alleviate or delay the progression?

G Tarantino, G Sinatti, V Citro, SJ Santini… - Internal and Emergency …, 2023 - Springer
Sarcopenia is a severe condition common to various chronic diseases and it is reckoned as
a major health problem. It encompasses many different molecular mechanisms that have …

Natural bioactive compounds useful in clinical management of metabolic syndrome

A Noce, M Di Lauro, F Di Daniele… - Nutrients, 2021 - mdpi.com
Metabolic syndrome (MetS) is a clinical manifestation characterized by a plethora of
comorbidities, including hyperglycemia, abdominal obesity, arterial hypertension, and …

Stool microRNA profiles reflect different dietary and gut microbiome patterns in healthy individuals

S Tarallo, G Ferrero, F De Filippis, A Francavilla… - Gut, 2022 - gut.bmj.com
Objectives MicroRNA (miRNA) profiles have been evaluated in several biospecimens in
relation to common diseases for which diet may have a considerable impact. We aimed at …

[HTML][HTML] Olea europaea L-derived secoiridoids: Beneficial health effects and potential therapeutic approaches

S Filardo, M Roberto, D Di Risola, L Mosca… - Pharmacology & …, 2024 - Elsevier
Over the years, health challenges have become increasingly complex and global and, at the
beginning of the 21st century, chronic diseases, including cardiovascular, neurological, and …

[HTML][HTML] Anti-angiogenic effects of oleacein and oleocanthal: New bioactivities of compounds from Extra Virgin Olive Oil

AD Marrero, J Ortega-Vidal, S Salido, L Castilla… - Biomedicine & …, 2023 - Elsevier
Phenolic compounds play a key role in the health benefits of Extra Virgin Olive Oil (EVOO).
Among these molecules, the focus has been recently put on (−)-oleocanthal and (−) …

[HTML][HTML] AGE/RAGE signaling-mediated endoplasmic reticulum stress and future prospects in non-coding RNA therapeutics for diabetic nephropathy

N Pathomthongtaweechai… - Biomedicine & …, 2020 - Elsevier
Disturbance of endoplasmic reticulum (ER) homeostasis triggered by the accumulation of
unfolded proteins and advanced glycation end-products (AGEs) plays a major role in …

Oleacein attenuates lipopolysaccharide-induced inflammation in THP-1-derived macrophages by the inhibition of TLR4/MyD88/NF-κB pathway

S Cirmi, A Maugeri, C Russo, L Musumeci… - International Journal of …, 2022 - mdpi.com
It is known that plant phenolic compounds exert anti-inflammatory activity through both anti-
oxidant effects and modulation of pivotal pro-inflammatory factors. Recently, Olea europaea …