Peptide nucleic acid (PNA) stands as one of the most successful artificial oligonucleotide
mimetics. Salient features include the stability of hybridization complexes (either as …

The substitution of primary or secondary alcohols with nucleophiles mediated by a redox
combination of a trialkylor triarylphosphine and a dialkyl azodicarboxylate is popularly …

Peptide nucleic acids (PNA) are deoxyribonucleic acid (DNA) mimics with a pseudopeptide
backbone. PNA is an extremely good structural mimic of DNA (or of ribonucleic acid [RNA]) …

This article presents the first evidence that the DNA base analogue 1, 3-diaza-2-
oxophenoxazine, tC O, is highly fluorescent, both as free nucleoside and incorporated in an …

We explore the potential of clamp-G nucleobase-modified peptide nucleic acids (cGPNAs)
as microRNA and messenger RNA inhibitors. For proof of concept, we target miR-155, which …

Pseudo-complementary oligonucleotides contain artificial nucleobases designed to reduce
duplex formation in the pseudo-complementary pair without compromising duplex formation …

Heterocycles incorporating a pyrimidopyrimidine scaffold have aroused great interest from
researchers in the field of medical chemistry because of their privileged biological activities; …

This tutorial review deals with recent advances in the use of phosphine-functionalised
polymers in organic synthesis. In the first part of the review, some recent applications of …

Fluorogenic oligonucleotide probes that can produce a change in fluorescence signal upon
binding to specific biomolecular targets, including nucleic acids as well as non-nucleic acid …

Conspectus The programmability of oligonucleotide hybridization offers an attractive
platform for the design of assemblies with emergent properties or functions. Developments …