Background Clinical interpretation of genetic variants in the context of the patient's
phenotype is becoming the largest component of cost and time expenditure for genome …

Structural variation (SV) plays a fundamental role in genome evolution and can underlie
inherited or acquired diseases such as cancer. Long-read sequencing technologies have …

Accurate detection of somatic structural variation (SV) in cancer genomes remains a
challenging problem. This is in part due to the lack of high-quality, gold-standard datasets …

Pollen fertility is a critical factor in seed development and crop breeding. Extensive studies
have explored the mechanisms of pollen fertility in model plants and economic crops …

In recent years, advances in the field of sequencing technologies have enabled the field of
population-scale sequencing studies. These studies aim to sequence and analyze a large …