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UBAP2L contributes to formation of P-bodies and modulates their association with stress granules
Stress triggers the formation of two distinct cytoplasmic biomolecular condensates: stress
granules (SGs) and processing bodies (PBs), both of which may contribute to stress …
granules (SGs) and processing bodies (PBs), both of which may contribute to stress …
Ubiquitin binding protein 2-like (UBAP2L): Is it so NICE after all?
Ubiquitin Binding Protein 2-like (UBAP2L, also known as NICE-4) is a ubiquitin-and RNA-
binding protein, highly conserved in metazoans. Despite its abundance, its functions have …
binding protein, highly conserved in metazoans. Despite its abundance, its functions have …
UBAP2L arginine methylation by PRMT1 modulates stress granule assembly
C Huang, Y Chen, H Dai, H Zhang, M ** these models. Often models are engineered to …
Identification of DNA methylation patterns predisposing for an efficient response to BCG vaccination in healthy BCG-naïve subjects
The protection against tuberculosis induced by the Bacille Calmette Guérin (BCG) vaccine is
unpredictable. In our previous study, altered DNA methylation pattern in peripheral blood …
unpredictable. In our previous study, altered DNA methylation pattern in peripheral blood …
DHHC protein family targets different subsets of glioma stem cells in specific niches
X Chen, L Hu, H Yang, H Ma, K Ye, C Zhao… - Journal of Experimental …, 2019 - Springer
Background Glioblastomas (GBM) comprise different subsets that exhibit marked
heterogeneity and plasticity, leading to a lack of success of genomic profiling in guiding the …
heterogeneity and plasticity, leading to a lack of success of genomic profiling in guiding the …
BMI1–UBR5 axis regulates transcriptional repression at damaged chromatin
BMI1 is a component of the Polycomb Repressive Complex 1 (PRC1), which plays a key
role in maintaining epigenetic silencing during development. BMI1 also participates in gene …
role in maintaining epigenetic silencing during development. BMI1 also participates in gene …
[HTML][HTML] UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1
AE Herlihy, S Boeing, JC Weems, J Walker… - DNA repair, 2022 - Elsevier
During transcription, RNA polymerase II (RNAPII) faces numerous obstacles, including DNA
damage, which can lead to stalling or arrest. One mechanism to contend with this situation is …
damage, which can lead to stalling or arrest. One mechanism to contend with this situation is …