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[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …
have been used in many different biomedical fields including diagnosis, biosensing and …
Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
Intracavity generation of glioma stem cell–specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy
Glioblastoma multiforme (GBM) remains incurable despite aggressive implementation of
multimodal treatments after surgical debulking. Almost all patients with GBM relapse within a …
multimodal treatments after surgical debulking. Almost all patients with GBM relapse within a …
Immunotherapy: a promising approach for glioma treatment
F Yasinjan, Y **ng, H Geng, R Guo, L Yang… - Frontiers in …, 2023 - frontiersin.org
Gliomas are the most prevalent primary malignant brain tumors worldwide, with
glioblastoma (GBM) being the most common and aggressive type. Despite two decades of …
glioblastoma (GBM) being the most common and aggressive type. Despite two decades of …
Understanding the immunosuppressive microenvironment of glioma: mechanistic insights and clinical perspectives
Glioblastoma (GBM), the predominant and primary malignant intracranial tumor, poses a
formidable challenge due to its immunosuppressive microenvironment, thereby confounding …
formidable challenge due to its immunosuppressive microenvironment, thereby confounding …
Engineered extracellular vesicle-delivered CRISPR/Cas9 for radiotherapy sensitization of glioblastoma
X Liu, Z Cao, W Wang, C Zou, Y Wang, L Pan, B Jia… - ACS …, 2023 - ACS Publications
Radiotherapy is a mainstay of glioblastoma (GBM) treatment; however, the development of
therapeutic resistance has hampered the efficacy of radiotherapy, suggesting that additional …
therapeutic resistance has hampered the efficacy of radiotherapy, suggesting that additional …
Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression
M Li, H Xu, Y Qi, Z Pan, B Li, Z Gao, R Zhao, H Xue… - Oncogene, 2022 - nature.com
Exosomes can selectively secrete harmful metabolic substances from cells to maintain
cellular homeostasis, and complex crosstalk occurs between exosomes and tumor …
cellular homeostasis, and complex crosstalk occurs between exosomes and tumor …
[HTML][HTML] Advances in diagnostic tools and therapeutic approaches for gliomas: a comprehensive review
Gliomas, a prevalent category of primary malignant brain tumors, pose formidable clinical
challenges due to their invasive nature and limited treatment options. The current …
challenges due to their invasive nature and limited treatment options. The current …
Receptor ligand-free mesoporous silica nanoparticles: a streamlined strategy for targeted drug delivery across the blood–brain barrier
Mesoporous silica nanoparticles (MSNs) represent a promising avenue for targeted brain
tumor therapy. However, the blood–brain barrier (BBB) often presents a formidable obstacle …
tumor therapy. However, the blood–brain barrier (BBB) often presents a formidable obstacle …
Immunotherapy in glioblastoma treatment: Current state and future prospects
SLR Pinheiro, FFB Lemos, HS Marques… - World Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Glioblastoma remains as the most common and aggressive malignant brain tumor, standing
with a poor prognosis and treatment prospective. Despite the aggressive standard care …
with a poor prognosis and treatment prospective. Despite the aggressive standard care …