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[HTML][HTML] Chronic inflammation and the hallmarks of aging
Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …
The role of neutrophil extracellular traps in acute lung injury
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …
morbidity and mortality. Neutrophils play a key role in the development of different forms of …
Mechanisms of cisplatin-induced acute kidney injury: pathological mechanisms, pharmacological interventions, and genetic mitigations
Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …
Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19
D Scozzi, M Cano, L Ma, D Zhou, JH Zhu… - JCI …, 2021 - pmc.ncbi.nlm.nih.gov
Background Mitochondrial DNA (MT-DNA) are intrinsically inflammatory nucleic acids
released by damaged solid organs. Whether circulating cell-free MT-DNA quantitation could …
released by damaged solid organs. Whether circulating cell-free MT-DNA quantitation could …
[HTML][HTML] Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular …
Z Chu, Q Huang, K Ma, X Liu, W Zhang, S Cui, Q Wei… - Bioactive Materials, 2023 - Elsevier
Neutrophil extracellular traps (NETs) have been considered a significant unfavorable factor
for wound healing in diabetes, but the mechanisms remain unclear. The therapeutic …
for wound healing in diabetes, but the mechanisms remain unclear. The therapeutic …
Signaling pathways and potential therapeutic targets in acute respiratory distress syndrome (ARDS)
Q Huang, Y Le, S Li, Y Bian - Respiratory Research, 2024 - Springer
Acute respiratory distress syndrome (ARDS) is a common condition associated with critically
ill patients, characterized by bilateral chest radiographical opacities with refractory …
ill patients, characterized by bilateral chest radiographical opacities with refractory …
Interaction between neutrophil extracellular traps and cardiomyocytes contributes to atrial fibrillation progression
L He, R Liu, H Yue, X Zhang, X Pan, Y Sun… - Signal transduction and …, 2023 - nature.com
Atrial fibrillation (AF) is a frequent arrhythmia associated with cardiovascular morbidity and
mortality. Neutrophil extracellular traps (NETs) are DNA fragments with cytoplasm proteins …
mortality. Neutrophil extracellular traps (NETs) are DNA fragments with cytoplasm proteins …
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal disease. Recent
findings have shown a marked metabolic reprogramming associated with changes in …
findings have shown a marked metabolic reprogramming associated with changes in …
Multifaceted mitochondria in innate immunity
E Marques, R Kramer, DG Ryan - npj Metabolic Health and Disease, 2024 - nature.com
The ability of mitochondria to transform the energy we obtain from food into cell
phosphorylation potential has long been appreciated. However, recent decades have seen …
phosphorylation potential has long been appreciated. However, recent decades have seen …
Biomimetic targeting Nanoadjuvants for sonodynamic and chronological multi‐immunotherapy against holistic biofilm‐related infections
L Wang, C Zhang, J Zhao, Z Zhu, J Wang… - Advanced …, 2024 - Wiley Online Library
Biofilm‐related infections (BRIs) present significant challenges owing to drug resistance,
adverse immune responses, and implant failure; however, current approaches inadequately …
adverse immune responses, and implant failure; however, current approaches inadequately …