Disseminated intravascular coagulation (DIC) is a condition characterized by systemic
activation of coagulation, potentially leading to thrombotic obstruction of small and midsize …

Despite continuous progress in medicine, sepsis remains the main cause of deaths in the
intensive care unit. Liver failure complicating sepsis/septic shock has a significant impact on …

The first consensus report of the working party of the Asian Pacific Association for the Study
of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published …

Patients with liver disease frequently acquire a complex disorder of hemostasis secondary to
their disease. Routine laboratory tests such as the prothrombin time and the platelet count …

Patients with chronic or acute liver failure frequently show profound abnormalities in their
hemostatic system. Whereas routine laboratory tests of hemostasis suggest these …

OBJECTIVE: To test in a prospective randomized study the hypothesis that use of
thromboelastography (TEG) decreases blood transfusion during major surgery. MATERIAL …

Several clinical conditions, in particular those associated with a systemic inflammatory
response, can cause some degree of activation of coagulation but when the procoagulant …

BACKGROUND & AIMS: Patients with acute liver injury/failure (ALI/ALF) are assumed to
have a bleeding diathesis on the basis of elevated INR; however, clinically significant …

BACKGROUND & AIMS: Patients with liver disease often show substantial changes in their
hemostatic system, which may aggravate further during liver transplantation. Recently …

Acute liver failure (ALF) is a syndrome of diverse etiology, in which patients without
previously recognized liver disease sustain a liver injury that results in rapid loss of hepatic …