From embryonic development, postnatal growth and adult homeostasis to reparative and
disease states, cells and tissues undergo constant changes in genome activity, cell fate …

The cornea, as a dynamic and responsive tissue, constantly interacts with mechanical forces
in order to maintain its structural integrity, barrier function, transparency and refractive …

Plastic deformation in cells and tissues has been found to play crucial roles in collective cell
migration, cancer metastasis, and morphogenesis. However, the fundamental question of …

Soft materials are usually defined as materials made of mesoscopic entities, often self-
organised, sensitive to thermal fluctuations and to weak perturbations. Archetypal examples …

Hydra regenerates one head when cut, but how forces sha** the head are coordinated
remains unclear. Soft compression of Hydra's head-regenerating tissues induces the …

Biological cells can actively tune their intracellular architecture according to their overall
shape. Here we explore the rheological implication of such coupling in a minimal model of a …

Wound repair, the closing of a hole, is inherently a physical process that requires the change
of shape of materials, in this case, cells and tissues. Not only is efficient and accurate wound …

Collectively moving cellular systems often contain a proportion of dead cells or non-motile
genotypes. When mixed, nematically aligning motile and non-motile agents are known to …

Bovine clinical mastitis is characterized by inflammation and immune responses, with
apoptosis of mammary epithelial cells as a cellular reaction to infection. PIEZO1, identified …

Complex tissue flows in epithelia are driven by intra-and inter-cellular processes that
generate, maintain, and coordinate mechanical forces. There has been growing evidence …