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Targeting the immune microenvironment for ovarian cancer therapy
F Blanc-Durand, L Clemence Wei ** captures the microanatomy and function of the human fallopian tube
The fallopian tubes play key roles in processes from pregnancy to ovarian cancer where
three-dimensional (3D) cellular and extracellular interactions are important to their …
three-dimensional (3D) cellular and extracellular interactions are important to their …
Aneuploidy landscape in precursors of ovarian cancer
Purpose: Serous tubal intraepithelial carcinoma (STIC) is now recognized as the main
precursor of ovarian high-grade serous carcinoma (HGSC). Other potential tubal lesions …
precursor of ovarian high-grade serous carcinoma (HGSC). Other potential tubal lesions …
[HTML][HTML] Opening the Black Box: Spatial Transcriptomics and the Relevance of Artificial Intelligence–Detected Prognostic Regions in High-Grade Serous Carcinoma
Image-based deep learning models are used to extract new information from standard
hematoxylin and eosin pathology slides; however, biological interpretation of the features …
hematoxylin and eosin pathology slides; however, biological interpretation of the features …
Spatial transcriptomics in cancer research and potential clinical impact: a narrative review
Spatial transcriptomics (ST) provides novel insights into the tumor microenvironment (TME).
ST allows the quantification and illustration of gene expression profiles in the spatial context …
ST allows the quantification and illustration of gene expression profiles in the spatial context …
Programmable Nanomodulators for Precision Therapy, Engineering Tumor Metabolism to Enhance Therapeutic Efficacy
Tumor metabolism is crucial in the continuous advancement and complex growth of cancer.
The emerging field of nanotechnology has made significant strides in enhancing the …
The emerging field of nanotechnology has made significant strides in enhancing the …
A cell atlas of the human fallopian tube throughout the menstrual cycle and menopause
The fallopian tube undergoes extensive molecular changes during the menstrual cycle and
menopause. We use single-cell RNA and ATAC sequencing to construct a comprehensive …
menopause. We use single-cell RNA and ATAC sequencing to construct a comprehensive …
Morphologic and Molecular Heterogeneity of High-grade Serous Carcinoma Precursor Lesions
Serous tubal intraepithelial carcinoma (STIC) is the fallopian tube precursor lesion for most
cases of pelvic high-grade serous carcinoma (HGSC). To date, the morphologic, molecular …
cases of pelvic high-grade serous carcinoma (HGSC). To date, the morphologic, molecular …
Exosomal IGFBP2 derived from highly metastatic promotes hepatocellular carcinoma metastasis by inducing epithelial mesenchymal transition
Y Zheng, W Li, Y Huang, H Cheng - Gene, 2024 - Elsevier
Liver cancer metastasis is the main cause of death in liver cancer patients. Exosomes, which
are small vesicles released by cancer cells, play a crucial role in the metastasis of cancer …
are small vesicles released by cancer cells, play a crucial role in the metastasis of cancer …