Chitosan is one of the natural cationic polymers with unique properties such as non-toxicity,
biodegradability, biocompatibility, environmentally friendly that has various biomedical …

Cartilage defects caused by mechanical tear and wear are challenging clinical problems.
Articular cartilage has unique load-bearing properties and limited self-repair ability. The …

Kartogenin, a small and heterocyclic molecule, has emerged as a promising therapeutic
agent for incorporation into biomaterials, owing to its unique physicochemical and biological …

We report a chitosan-based nanocomposite thermogel with superior shear modulus
resembling that of cartilage and dual pro-chondrogenic and anti-inflammatory functions. Two …

Methods that leverage bone marrow mesenchymal stem cells (BMSCs) and stimulating
factor kartogenin (KGN) for chondrocyte differentiation have paved the way for cartilage …

Articular cartilage (AC) plays an unquestionable role in joint movements but unfortunately
the healing capacity is restricted due to its avascular and acellular nature. While cartilage …