A review of biological applications of transition metal complexes incorporating N-acylhydrazones
I Hamzi - Mini-Reviews in Organic Chemistry, 2022 - ingentaconnect.com
In view of the crucial importance of the bioactivities of N-acylhydrazone derivatives and their
corresponding metal complexes, N-acylhydrazones have recently attracted the attention of …
corresponding metal complexes, N-acylhydrazones have recently attracted the attention of …
Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3, 5-disubstituted isoxazole compounds based on benznidazole
DB Carvalho, PAN Costa, GB Portapilla… - European Journal of …, 2023 - Elsevier
Chagas disease and leishmaniasis are neglected diseases of high priority as a public health
problem. Pharmacotherapy is based on the administration of a few drugs, which exhibit …
problem. Pharmacotherapy is based on the administration of a few drugs, which exhibit …
[HTML][HTML] Bismuth (III) complexes with 2-acetylpyridine-and 2-benzoylpyridine-derived hydrazones: Antimicrobial and cytotoxic activities and effects on the clonogenic …
IP Ferreira, EDL Piló, AA Recio-Despaigne… - Bioorganic & medicinal …, 2016 - Elsevier
Abstract Complexes [Bi (2AcPh) Cl 2]· 0.5 H 2 O (1),[Bi (2AcpClPh) Cl 2](2),[Bi (2AcpNO 2
Ph) Cl 2](3),[Bi (2AcpOHPh) Cl 2]· 2H 2 O (4),[Bi (H2BzPh) Cl 3]· 2H 2 O (5),[Bi (H2BzpClPh) …
Ph) Cl 2](3),[Bi (2AcpOHPh) Cl 2]· 2H 2 O (4),[Bi (H2BzPh) Cl 3]· 2H 2 O (5),[Bi (H2BzpClPh) …
Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor
Transient receptor potential vanilloid 6 (TRPV6) is a calcium channel implicated in
multifactorial diseases and overexpressed in numerous cancers. We recently reported the …
multifactorial diseases and overexpressed in numerous cancers. We recently reported the …
Organometallic N‐acylhydrazones of 5‐nitrofuran and 5‐nitrothiophene based: Synthesis, electrochemical, antiparasitic evaluation, and computational study
In searching for new therapeutic agents for treating American trypanosomiasis and Human
African trypanosomiasis, four nitroheterocyclic acylhydrazones of general formulae [R1‐CH …
African trypanosomiasis, four nitroheterocyclic acylhydrazones of general formulae [R1‐CH …
Structural design, synthesis and substituent effect of hydrazone-N-acylhydrazones reveal potent immunomodulatory agents
CS Meira, JM dos Santos Filho, CC Sousa… - Bioorganic & medicinal …, 2018 - Elsevier
(Nitrophenyl) hydrazone derivatives of N-acylhydrazone were synthesized and screened for
suppress lymphocyte proliferation and nitrite inhibition in macrophages. Compared to an …
suppress lymphocyte proliferation and nitrite inhibition in macrophages. Compared to an …
Identification of LASSBio-1945 as an inhibitor of SARS-CoV-2 main protease (M PRO) through in silico screening supported by molecular docking and a fragment …
In December 2019, an infectious disease was detected in Wuhan, China, caused by a new
pathogenic coronavirus, named SARS-CoV-2. It spread very rapidly, and on March 11th of …
pathogenic coronavirus, named SARS-CoV-2. It spread very rapidly, and on March 11th of …
Synthesis, structure, chemical stability, and in vitro cytotoxic properties of novel quinoline-3-carbaldehyde hydrazones bearing a 1, 2, 4-triazole or benzotriazole …
M Korcz, F Sączewski, PJ Bednarski, A Kornicka - Molecules, 2018 - mdpi.com
A small library of novel quinoline-3-carbaldehyde hydrazones (Series 1), acylhydrazones
(Series 2), and arylsulfonylhydrazones (Series 3) bearing either a 1, 2, 4-triazole or …
(Series 2), and arylsulfonylhydrazones (Series 3) bearing either a 1, 2, 4-triazole or …
Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N-Acylhydrazone Derivatives of Pyrrolo[3,4-d]pyridazinone as Dual COX/LOX …
J Mikus, P Świątek, P Przybyła, E Krzyżak, A Marciniak… - Molecules, 2023 - mdpi.com
Secure and efficient treatment of diverse pain and inflammatory disorders is continually
challenging. Although NSAIDs and other painkillers are well-known and commonly …
challenging. Although NSAIDs and other painkillers are well-known and commonly …
Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives
ADT de Oliveira Moraes, MDS de Miranda… - Bioorganic & Medicinal …, 2018 - Elsevier
The objective of this work was to obtain and evaluate anti-inflammatory in vitro, in vivo and in
silico potential of novel indole-N-acylhydrazone derivatives. In total, 10 new compounds (3a …
silico potential of novel indole-N-acylhydrazone derivatives. In total, 10 new compounds (3a …