Glycosidic flavonoids and their potential applications in cancer research: A review
A Abusaliya, SE Ha, PB Bhosale, HH Kim… - Molecular & Cellular …, 2022 - Springer
Purpose of review Every year, the cancer patient registry increases, and the leading cause
of death in a global context. Plant-based molecules are gaining attention in cancer research …
of death in a global context. Plant-based molecules are gaining attention in cancer research …
Mechanistic action of cell cycle arrest and intrinsic apoptosis via inhibiting Akt/mTOR and activation of p38-MAPK signaling pathways in Hep3B liver cancer cells by …
Hepatocellular carcinoma (HCC) has a poor prognosis and a low survival rate. Drugs
without side effects are desperately needed since chemotherapy has a negative effect on …
without side effects are desperately needed since chemotherapy has a negative effect on …
Pretreatment with rosavin attenuates PM2. 5‐induced lung injury in rats through antiferroptosis via PI3K/Akt/Nrf2 signaling pathway
Y Wang, S Zhao, N Jia, Z Shen, D Huang… - Phytotherapy …, 2023 - Wiley Online Library
Inflammation and oxidative stress caused by fine particulate matter (PM2. 5) increase the
incidence and mortality rates of respiratory disorders. Rosavin is the main chemical …
incidence and mortality rates of respiratory disorders. Rosavin is the main chemical …
The potential therapeutic properties of prunetin against human health complications: a review of medicinal importance and pharmacological activities
K Patel, DK Patel - Drug Metabolism and Bioanalysis Letters …, 2022 - ingentaconnect.com
Background: Flavonoids are polyphenolic compounds found to be present in nature and
abundant in flowers and fruits. Flavonoidal class phytochemicals have gained interest in the …
abundant in flowers and fruits. Flavonoidal class phytochemicals have gained interest in the …
[HTML][HTML] Effects of catechin on the malignant biological behavior of gastric cancer cells through the PI3K/Akt signaling pathway
Y Ding, H Li, S Cao, Y Yu - Toxicology and Applied Pharmacology, 2024 - Elsevier
Catechin is a kind of flavonoids, mainly derived from the plant Camellia sinensis. It has a
strong antioxidant effect, and it also has significant therapeutic effects on anti-cancer, anti …
strong antioxidant effect, and it also has significant therapeutic effects on anti-cancer, anti …
Network pharmacology and experimental validation to explore the effect and mechanism of kanglaite injection against triple-negative breast cancer
M Zhao, L Fu, P Xu, T Wang, P Li - Drug Design, Development and …, 2023 - Taylor & Francis
Purpose Kanglaite injection (KLTi), made of Coix seed oil, has been shown to be effective in
the treatment of numerous cancers. However, the anticancer mechanism requires further …
the treatment of numerous cancers. However, the anticancer mechanism requires further …
Investigations of nitazoxanide molecular targets and pathways for the treatment of hepatocellular carcinoma using network pharmacology and molecular docking
Nitazoxanide has been investigated for colorectal cancer and breast cancer. However, its
molecular targets and pathways have not yet been explored for hepatocellular carcinoma …
molecular targets and pathways have not yet been explored for hepatocellular carcinoma …
Src is a target molecule of mannose against pancreatic cancer cells growth in vitro & in vivo
J **e, S Wu, W Liao, J Ning, K Ding - Glycobiology, 2023 - academic.oup.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant cancer with limited
treatment options. Mannose, a common monosaccharide taken up by cells through the same …
treatment options. Mannose, a common monosaccharide taken up by cells through the same …
A network pharmacology-and transcriptomics-based investigation reveals an inhibitory role of β-sitosterol in glioma via the EGFR/MAPK signaling pathway: Inhibitory …
Y **e, Z Chen, S Li, M Yan, W He, L Li… - Acta Biochimica et …, 2023 - pmc.ncbi.nlm.nih.gov
Glioma is characterized by rapid cell proliferation, aggressive invasion, altered apoptosis
and a poor prognosis. β-Sitosterol, a kind of phytosterol, has been shown to possess …
and a poor prognosis. β-Sitosterol, a kind of phytosterol, has been shown to possess …
[HTML][HTML] Investigation of prunetrin induced G2/M cell cycle arrest and apoptosis via Akt/mTOR/MAPK pathways in hepatocellular carcinoma cells
Hepatocellular carcinoma (HCC) stands as a leading cause of mortality, and despite recent
advancements in the overall survival rates, the prognosis remains dismal. Prunetin 4-O …
advancements in the overall survival rates, the prognosis remains dismal. Prunetin 4-O …