The contributions of cancer-testis and developmental genes to the pathogenesis of keratinocyte carcinomas

B Ramchatesingh, J Gantchev, A Martínez Villarreal… - Cancers, 2022 - mdpi.com
Simple Summary In addition to mutations, ectopically-expressed genes are emerging as
important contributors to cancer development. Efforts to characterize the expression patterns …

IL‐17A promotes cell migration and invasion of glioblastoma cells via activation of PI 3K/AKT signalling pathway

Q Zheng, S Diao, Q Wang, C Zhu, X Sun… - Journal of cellular …, 2019 - Wiley Online Library
Glioblastomas (GBM s) are the most common of both benign and malignant primary brain
tumours, in which the inflammatory and immunologic abnormalities are involved. Interleukin …

Emerging biological functions of Twist1 in cell differentiation

M Tu, B Ge, J Li, Y Pan, B Zhao, J Han… - Developmental …, 2025 - Wiley Online Library
Twist1 is required for embryonic development and expresses after birth in mesenchymal
stem cells derived from mesoderm, where it governs mesenchymal cell development. As a …

MiR-33a-5p inhibits the growth and metastasis of melanoma cells by targeting SNAI2.

ZR Zhang, N Yang - Neoplasma, 2020 - search.ebscohost.com
MicroRNAs have been verified as critical regulators in the development of melanoma. miR-
33a-5p was significantly downregulated in melanoma, however, the specific role and …

Altered expression of E-Cadherin-related transcription factors indicates partial epithelial-mesenchymal transition in aggressive meningiomas

M Wallesch, D Pachow, C Blücher, R Firsching… - Journal of the …, 2017 - Elsevier
E-Cadherin has been suggested to be involved in meningioma progression but is also
known as a key player of epithelial to mesenchymal transition (EMT). We wondered whether …

Twist1 as a target for prevention of cutaneous squamous cell carcinoma

T Wang, O Rho, F Eguiarte‐Solomon… - Molecular …, 2023 - Wiley Online Library
Cutaneous squamous cell carcinoma (cSCC) represents an important clinical problem
requiring novel approaches for both prevention and treatment. The transcription factor, Twist …

Decreased Sox2 messenger RNA expression in basal cell carcinoma

R Ahmadi-Beni, F Vand-Rajabpour… - Indian Journal of …, 2020 - journals.lww.com
Background: Sox2, zeb1, and p21 have been implicated in aggressive behavior of
squamous cell carcinoma (SCC) and melanoma. However, their expression level in basal …

[HTML][HTML] Whole‑genome identification and systematic analysis of lncRNA‑mRNA co‑expression profiles in patients with cutaneous basal cell carcinoma

J Zhang, X Zhou, C Zhu, Y Hu, R Li… - Molecular …, 2021 - spandidos-publications.com
Cutaneous basal cell carcinoma (BCC) is a common subtype of malignant skin tumor with
low invasiveness. Early diagnosis and treatment of BCC and the identification of specific …

Upregulation of SNAI2 and SOX9 mRNA versus downregulation of eight other EMT/stemness related genes in basal cell carcinoma

F Vand‐Rajabpour… - British Journal of …, 2019 - academic.oup.com
DEAR EDITOR, Basal cell carcinoma (BCC) is the most common malignancy among fair-
skinned people. In contrast to other types of cancer, BCC has the lowest rate of metastasis …

Immunohistochemical overexpression of TWIST1 in metastatic melanomas compared with primary melanomas and nevi

KMPA Coelho, J Stall, BL Silva… - Journal …, 2024 - ojs.latinamericanpublicacoes.com.br
Melanoma is an aggressive neoplasia with poor prognosis when not identified and treated
early. Phenotypic changes related to melanocytic cell invasion and metastasis have been …