Glioma targeted therapy: insight into future of molecular approaches

K Yang, Z Wu, H Zhang, N Zhang, W Wu, Z Wang… - Molecular Cancer, 2022 - Springer
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Current state of immunotherapy for glioblastoma

M Lim, Y **a, C Bettegowda, M Weller - Nature reviews Clinical …, 2018 - nature.com
Glioma is the most common primary cancer of the central nervous system, and around 50%
of patients present with the most aggressive form of the disease, glioblastoma. Conventional …

[HTML][HTML] Immunotherapy for glioma: current management and future application

S Xu, L Tang, X Li, F Fan, Z Liu - Cancer letters, 2020 - Elsevier
Gliomas are intrinsic brain tumors that originate from neuroglial progenitor cells.
Conventional therapies, including surgery, chemotherapy, and radiotherapy, have achieved …

Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy

TA Patente, MP Pinho, AA Oliveira… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …

Antitumour dendritic cell vaccination in a priming and boosting approach

A Harari, M Graciotti, M Bassani-Sternberg… - Nature Reviews Drug …, 2020 - nature.com
Mobilizing antitumour immunity through vaccination potentially constitutes a powerful
anticancer strategy but has not yet provided robust clinical benefits in large patient …

Neoantigen vaccine: an emerging tumor immunotherapy

M Peng, Y Mo, Y Wang, P Wu, Y Zhang, F **ong… - Molecular cancer, 2019 - Springer
Genetic instability of tumor cells often leads to the occurrence of a large number of
mutations, and expression of non-synonymous mutations can produce tumor-specific …

Glioma: molecular signature and crossroads with tumor microenvironment

L Barthel, M Hadamitzky, P Dammann… - Cancer and Metastasis …, 2022 - Springer
In patients with glioblastoma, the average survival time with current treatments is short,
mainly due to recurrences and resistance to therapy. This insufficient treatment success is, in …

Potential strategies overcoming the temozolomide resistance for glioblastoma

S Jiapaer, T Furuta, S Tanaka, T Kitabayashi… - Neurologia medico …, 2018 - jstage.jst.go.jp
Glioblastoma (GBM) is a highly malignant type of primary brain tumor with a high mortality
rate. Although the current standard therapy consists of surgery followed by radiation and …

Current immunotherapies for glioblastoma multiforme

B Huang, X Li, Y Li, J Zhang, Z Zong… - Frontiers in …, 2021 - frontiersin.org
Glioblastoma multiforme (GBM) is the most common and aggressive malignant tumor found
in the central nervous system. Currently, standard treatments in the clinic include maximal …

Cancer stem cells and immunosuppressive microenvironment in glioma

Q Ma, W Long, C **ng, J Chu, M Luo… - Frontiers in …, 2018 - frontiersin.org
Glioma is one of the most common malignant tumors of the central nervous system and is
characterized by extensive infiltrative growth, neovascularization, and resistance to various …