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Pyrimidine-based antimalarials: design strategies and antiplasmodial effects
K Singh, T Kaur - MedChemComm, 2016 - pubs.rsc.org
Pyrimidine-containing compounds have attracted great attention because of their biological
effects, therapeutic potential and flexibility in structural modification by way of diversifying …
effects, therapeutic potential and flexibility in structural modification by way of diversifying …
Recent developments in optical resolution
R Siedlecka - Tetrahedron, 2013 - Elsevier
Resolution methods of racemic or enriched mixtures are continuously exploited and
developed, particularly to obtain both enantiomers of chiral compounds. This compilation …
developed, particularly to obtain both enantiomers of chiral compounds. This compilation …
Synthesis of 2, 6-Diaminotriptycene Conjugates with Chiral Auxiliaries: Towards the Scalable Resolution of Crucial Triptycene Intermediates
Triptycenes are tridimensional molecular scaffolds with interesting properties for
applications in materials science: molecular rigidity and preorganization, tailorable …
applications in materials science: molecular rigidity and preorganization, tailorable …
The hybrid antimalarial approach
The incidence and prevalence of malaria presents a much worrying trend and seems to
negate the global efforts to control malarial infection. This is in part attributed to a smaller …
negate the global efforts to control malarial infection. This is in part attributed to a smaller …
Immobilized gelatin–λ–carrageenan on magnetite nanoparticles as an efficient organocatalyst for enantioselective Biginelli reaction
A facile method for preparation of stabilized and functionalized nanoparticles (NPs) from
magnetite by successive application of blended natural polymers (gelatin and λ …
magnetite by successive application of blended natural polymers (gelatin and λ …
Enantioselective N‐Acylation of Biginelli Dihydropyrimidines by Oxidative NHC Catalysis
The oxidative N‐acylation reaction of 3, 4‐dihydropyrimidin‐2‐(1H)‐ones (DHPMs) with
enals and N‐heterocyclic carbene (NHC) catalysts is described. The reaction proceeds in …
enals and N‐heterocyclic carbene (NHC) catalysts is described. The reaction proceeds in …
An efficient green protocol for the preparation of acetoacetamides and application of the methodology to a one-pot synthesis of Biginelli dihydropyrimidines …
FHS Gama, ROMA de Souza, SJ Garden - RSC Advances, 2015 - pubs.rsc.org
The present study describes the preparation of N-aryl-(15) and N-alkyl-(17)
acetoacetamides, in good to excellent yields, using both conventional and microwave …
acetoacetamides, in good to excellent yields, using both conventional and microwave …
Unexpected One‐pot Synthesis of Novel 2‐Aminopyrimidine‐4‐ones under Microwave Irradiation
H Kefayati, SM Mirfarhadi… - Journal of the Chinese …, 2015 - Wiley Online Library
One‐pot, three‐component condensation of guanidine, ethylbenzoylacetate and various
aromatic aldehydes in the presence of NaHCO3 have been investigated by microwave …
aromatic aldehydes in the presence of NaHCO3 have been investigated by microwave …
[PDF][PDF] One-pot synthesis of new derivatives of 3, 4-dihydropyrimidinone, and substituted imidazolin-2-ones
Three-component condensation of arylglyoxals, acetylacetone and urea in EtOH in the
presence of small amounts of HOAc gives rise to 5-acetyl-4-aroyl-6-methyl-3, 4 …
presence of small amounts of HOAc gives rise to 5-acetyl-4-aroyl-6-methyl-3, 4 …
Highly Regioselective Addition of Organozinc Reagents to 2‐Oxo‐1,2‐dihydropyrimidine‐5‐carboxylates Activated by BF3·OEt2: Synthesis of 2‐Oxo‐1,2,3,4 …
The incorporation of alkyl as well as phenyl groups at C‐4, a key position of 2‐oxo‐1, 2, 3, 4‐
tetrahydropyrimidine‐5‐carboxylates, responsible for antagonist/agonist switching of the …
tetrahydropyrimidine‐5‐carboxylates, responsible for antagonist/agonist switching of the …