Hydrogel drug delivery systems for minimally invasive local immunotherapy of cancer

AS Mikhail, R Morhard, M Mauda-Havakuk… - Advanced drug delivery …, 2023 - Elsevier
Although systemic immunotherapy has achieved durable responses and improved survival
for certain patients and cancer types, low response rates and immune system-related …

Recent advances in regenerative biomaterials

D Cao, J Ding - Regenerative Biomaterials, 2022 - academic.oup.com
Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

Polymeric hydrogels-based materials for wastewater treatment

M Ahmaruzzaman, P Roy, A Bonilla-Petriciolet… - Chemosphere, 2023 - Elsevier
Low-cost and reliable wastewater treatment is a relevant issue worldwide to reduce the
concentration of environmental pollutants. Industrial effluents containing dyes, heavy metals …

Sustained release of nitric oxide and cascade generation of reactive nitrogen/oxygen species via an injectable hydrogel for tumor synergistic therapy

Y Wang, X Yang, X Chen, X Wang… - Advanced Functional …, 2022 - Wiley Online Library
Reactive nitrogen species (RNS) generated via the reaction of nitric oxide (NO) with reactive
oxygen species (ROS) are more lethal than ROS, and thus RNS‐mediated therapy has great …

[HTML][HTML] Sustained co-delivery of 5-fluorouracil and cis-platinum via biodegradable thermo-sensitive hydrogel for intraoperative synergistic combination chemotherapy …

W Chen, K Shi, J Liu, P Yang, R Han, M Pan, L Yuan… - Bioactive materials, 2023 - Elsevier
Gastric cancer is the fifth most common cancer and the third leading cause of cancer death
worldwide, posing a severe threat to human health. Surgical resection remains the most …

[HTML][HTML] A beginner's guide to the characterization of hydrogel microarchitecture for cellular applications

FD Martinez-Garcia, T Fischer, A Hayn, CT Mierke… - Gels, 2022 - mdpi.com
The extracellular matrix (ECM) is a three-dimensional, acellular scaffold of living tissues.
Incorporating the ECM into cell culture models is a goal of cell biology studies and requires …

[HTML][HTML] Biomaterial–related cell microenvironment in tissue engineering and regenerative medicine

J Gao, X Yu, X Wang, Y He, J Ding - Engineering, 2022 - Elsevier
An appropriate cell microenvironment is key to tissue engineering and regenerative
medicine. Revealing the factors that influence the cell microenvironment is a fundamental …

[HTML][HTML] Recent advances on thermosensitive hydrogels-mediated precision therapy

H Chen, J Xu, J Sun, Y Jiang, W Zheng, W Hu… - Asian Journal of …, 2024 - Elsevier
Precision therapy has become the preferred choice attributed to the optimal drug
concentration in target sites, increased therapeutic efficacy, and reduced adverse effects …

Image-guided intratumoral immunotherapy: Develo** a clinically practical technology

A Som, JG Rosenboom, A Chandler, RA Sheth… - Advanced drug delivery …, 2022 - Elsevier
Immunotherapy has revolutionized the contemporary oncology landscape, with durable
responses possible across a range of cancer types. However, the majority of cancer patients …

[HTML][HTML] Autophagy inhibition mediated via an injectable and NO-releasing hydrogel for amplifying the antitumor efficacy of mild magnetic hyperthermia

Y Wang, X Chen, Z Chen, X Wang, H Wang, H Zhai… - Bioactive Materials, 2024 - Elsevier
While mild hyperthermia holds great potential in the treatment of solid tumors, the thermal
stress-triggered self-repairing autophagy significantly compromises its efficacy. To …