Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important
functions in the regulation of growth and survival of certain cell types during embryonal …

Platelet‐derived growth factor (PDGF) isoforms and their receptors have important roles
during embryogenesis, particularly in the development of various mesenchymal cell types in …

Prostate cancer (PCa) is by far the most commonly diagnosed cancer in men worldwide.
Despite sensitivity to androgen deprivation, patients with advanced disease eventually …

Metabolic reprogramming is an important driver of tumor progression; however, the
metabolic regulators of tumor cell motility and metastasis are not understood. Here, we show …

The receptors for platelet-derived growth factor (PDGF) and stem cell factor (SCF) are
members of the type III class of PTK receptors, which are characterized by five Ig-like …

Angiogenesis is known as one of the hallmarks in cancer which could play a key role in
providing oxygen and nutrients for tumor cells. It has been shown that tumor cannot grow …

Bone represents a common site of metastasis from several solid tumours, including breast,
prostate and lung malignancies. The onset of bone metastases (BM) is associated not only …

Despite the progress made in the early detection and treatment of prostate adenocarcinoma,
the metastatic lesions from this tumor are incurable. We used genome-wide expression …

Prostate cancer (PCa) is an increasingly prevalent health problem in the developed world.
Effective treatment options exist for localized PCa, but metastatic PCa has fewer treatment …

The bone microenvironment provides a fertile soil for cancer cells. It is therefore not
surprising that the skeleton is a frequent site of cancer metastasis. It is believed that …