The emergence of lncRNAs in cancer biology
The discovery of numerous noncoding RNA (ncRNA) transcripts in species from yeast to
mammals has dramatically altered our understanding of cell biology, especially the biology …
mammals has dramatically altered our understanding of cell biology, especially the biology …
Emerging roles of long non‐coding RNA in cancer
A Sanchez Calle, Y Kawamura, Y Yamamoto… - Cancer …, 2018 - Wiley Online Library
Since comprehensive analysis of the mammalian genome revealed that the majority of
genomic products are transcribed in long non‐coding RNA (lnc RNA), increasing attention …
genomic products are transcribed in long non‐coding RNA (lnc RNA), increasing attention …
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer
The human genome is replete with long non-coding RNAs (lncRNA), many of which are
transcribed and likely to have a functional role. Microarray analysis of> 23 000 lncRNAs …
transcribed and likely to have a functional role. Microarray analysis of> 23 000 lncRNAs …
MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …
molecular biology assuming protein-coding genes as unique functional biological effectors …
[HTML][HTML] The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine
P Qi, X Du - Modern pathology, 2013 - Elsevier
The conventional view of gene regulation in biology has centered around protein-coding
genes via the central dogma of DNA→ mRNA→ protein. The discovery of thousands of long …
genes via the central dogma of DNA→ mRNA→ protein. The discovery of thousands of long …
Large non-coding RNAs: missing links in cancer?
Cellular homeostasis is achieved by the proper balance of regulatory networks that if
disrupted can lead to cellular transformation. These cell circuits are fine-tuned and …
disrupted can lead to cellular transformation. These cell circuits are fine-tuned and …
Long non-coding RNA: a new player in cancer
Emerging evidence showed that long non-coding RNAs (lncRNAs) play important roles in a
wide range of biological processes and dysregulated lncRNAs are involved in many …
wide range of biological processes and dysregulated lncRNAs are involved in many …
[HTML][HTML] Regulation of lncRNA and its role in cancer metastasis
J Li, H Meng, Y Bai, K Wang - Oncology research, 2016 - ncbi.nlm.nih.gov
Metastasis is the primary cause of cancer-related death all over the world. Metastasis is a
process by which cancer spreads from the place at which it first arose to distant locations in …
process by which cancer spreads from the place at which it first arose to distant locations in …
Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets
V Kameswaran, NC Bramswig, LB McKenna, M Penn… - Cell metabolism, 2014 - cell.com
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the
insulin-producing β cells in the endocrine pancreas to overcome insulin resistance in …
insulin-producing β cells in the endocrine pancreas to overcome insulin resistance in …
Non-coding RNAs as mediators of epigenetic changes in malignancies
S Kumar, EA Gonzalez, P Rameshwar, JP Etchegaray - Cancers, 2020 - mdpi.com
Simple Summary This review discusses the role of non-coding RNAs (ncRNAs) in cancer
epigenetics, mostly focusing on how deregulated microRNAs (miRNAs) and long non …
epigenetics, mostly focusing on how deregulated microRNAs (miRNAs) and long non …