Brain GABA levels across psychiatric disorders: A systematic literature review and meta‐analysis of 1H‐MRS studies
RR Schür, LWR Draisma, JP Wijnen… - Human brain …, 2016 - Wiley Online Library
The inhibitory gamma‐aminobutyric acid (GABA) system is involved in the etiology of most
psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major …
psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major …
Psychological and biological mechanisms linking trauma with cardiovascular disease risk
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, and
experiences of psychological trauma have been associated with subsequent CVD onset …
experiences of psychological trauma have been associated with subsequent CVD onset …
Oxidative stress, inflammation, and neuroprogression in chronic PTSD
Posttraumatic stress disorder is a serious and often disabling syndrome that develops in
response to a traumatic event. Many individuals who initially develop the disorder go on to …
response to a traumatic event. Many individuals who initially develop the disorder go on to …
Prefrontal excitatory/inhibitory balance in stress and emotional disorders: evidence for over-inhibition
Chronic stress-induced emotional disorders like anxiety and depression involve imbalances
between the excitatory glutamatergic system and the inhibitory GABAergic system in the …
between the excitatory glutamatergic system and the inhibitory GABAergic system in the …
Is post-traumatic stress disorder associated with premature senescence? A review of the literature
JB Lohr, BW Palmer, CA Eidt, S Aailaboyina… - The American Journal of …, 2015 - Elsevier
Objective Post-traumatic stress disorder (PTSD) has major public health significance.
Evidence that PTSD may be associated with premature senescence (early or accelerated …
Evidence that PTSD may be associated with premature senescence (early or accelerated …
Single-prolonged stress: a review of two decades of progress in a rodent model of post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is a common, costly, and often debilitating psychiatric
condition. However, the biological mechanisms underlying this disease are still largely …
condition. However, the biological mechanisms underlying this disease are still largely …
Glutamate dysregulation and glutamatergic therapeutics for PTSD: Evidence from human studies
Posttraumatic stress disorder (PTSD) is a chronic and debilitating psychiatric disorder
afflicting millions of individuals across the world. While the availability of robust …
afflicting millions of individuals across the world. While the availability of robust …
Glutathione in the human brain: Review of its roles and measurement by magnetic resonance spectroscopy
We review the transport, synthesis and catabolism of glutathione in the brain as well as its
compartmentation and biochemistry in different brain cells. The major reactions involving …
compartmentation and biochemistry in different brain cells. The major reactions involving …
Sensitivity of the prefrontal GABAergic system to chronic stress in male and female mice: relevance for sex differences in stress-related disorders
Stress-induced modifications of the prefrontal cortex (PFC) are believed to contribute to the
onset of mood disorders, such as depression and anxiety, which are more prevalent in …
onset of mood disorders, such as depression and anxiety, which are more prevalent in …
Threshold Modulative Artificial GABAergic Nociceptor
Gamma‐aminobutyric acid (GABA) is a crucial inhibitory neurotransmitter of the central
nervous system. It modifies the signal threshold of the nociceptor, allowing it to react to …
nervous system. It modifies the signal threshold of the nociceptor, allowing it to react to …