Cell therapy: types, regulation, and clinical benefits

AEH El-Kadiry, M Rafei, R Shammaa - Frontiers in Medicine, 2021 - frontiersin.org
Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

Stem cell-derived exosomes: a new strategy of neurodegenerative disease treatment

N Fayazi, M Sheykhhasan, S Soleimani Asl… - Molecular …, 2021 - Springer
Short-term symptomatic treatment and dose-dependent side effects of pharmacological
treatment for neurodegenerative diseases have forced the medical community to seek an …

Wharton jelly-derived mesenchymal stem cell exosomes induce apoptosis and suppress EMT signaling in cervical cancer cells as an effective drug carrier system of …

BI Abas, GM Demirbolat, O Cevik - PloS one, 2022 - journals.plos.org
Mesenchymal stem cells can be obtained and multiplied from various sources and have a
very high capacity to release exosomes. Exosomes are nano-sized extracellular vesicles …

Mitochondrial plasticity in cell fate regulation

A Bahat, A Gross - Journal of Biological Chemistry, 2019 - ASBMB
Mitochondria are considered highly plastic organelles. This plasticity enables the
mitochondria to undergo morphological and functional changes in response to cellular …

[HTML][HTML] Optimizing CRISPR/Cas9 precision: Mitigating off-target effects for safe integration with photodynamic and stem cell therapies in cancer treatment

JPJ Merlin, H Abrahamse - Biomedicine & Pharmacotherapy, 2024 - Elsevier
CRISPR/Cas9 precision genome editing has revolutionized cancer treatment by introducing
specific alterations to the cancer genome. But the therapeutic potential of CRISPR/Cas9 is …

Mesenchymal stem cell-derived exosomes as new tools for delivery of miRNAs in the treatment of cancer

A Dalmizrak, O Dalmizrak - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Although ongoing medical research is working to find a cure for a variety of cancers, it
continues to be one of the major causes of death worldwide. Chemotherapy and …

A review of recent advances in 3D bioprinting with an eye on future regenerative therapies in veterinary medicine

C Jamieson, P Keenan, DA Kirkwood, S Oji… - Frontiers in veterinary …, 2021 - frontiersin.org
3D bioprinting is a rapidly evolving industry that has been utilized for a variety of biomedical
applications. It differs from traditional 3D printing in that it utilizes bioinks comprised of cells …

Effect of polymeric matrix stiffness on osteogenic differentiation of mesenchymal stem/progenitor cells: concise review

AA El-Rashidy, S El Moshy, IA Radwan, D Rady… - Polymers, 2021 - mdpi.com
Mesenchymal stem/progenitor cells (MSCs) have a multi-differentiation potential into
specialized cell types, with remarkable regenerative and therapeutic results. Several factors …

A review of placenta and umbilical cord-derived stem cells and the immunomodulatory basis of their therapeutic potential in bronchopulmonary dysplasia

WK Chia, FC Cheah, NH Abdul Aziz… - Frontiers in …, 2021 - frontiersin.org
Bronchopulmonary dysplasia (BPD) is a devastating lung disorder of preterm infants as a
result of an aberrant reparative response following exposures to various antenatal and …

Stem cell-derived exosomes potential therapeutic roles in cardiovascular diseases

S Jayaraman, D Gnanasampanthapandian… - Frontiers in …, 2021 - frontiersin.org
Owing to myocardial abnormalities, cardiac ailments are considered to be the major cause
of morbidity and mortality worldwide. According to a recent study, membranous vesicles that …