Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …
physiology and pathology in living systems, making significant contributions to life science …
Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species
KG Fosnacht, MD Pluth - Chemical Reviews, 2024 - ACS Publications
Hydrogen sulfide (H2S) is not only a well-established toxic gas but also an important small
molecule bioregulator in all kingdoms of life. In contemporary biology, H2S is often classified …
molecule bioregulator in all kingdoms of life. In contemporary biology, H2S is often classified …
Strategic Design of Luminescent Rhenium (I), Ruthenium (II), and Iridium (III) Complexes as Activity‐Based Probes for Bioimaging and Biosensing
The rapid development of responsive fluorescent probes has advanced optical imaging for
biological research and biomedical applications. Among different sensing strategies, activity …
biological research and biomedical applications. Among different sensing strategies, activity …
Photoinduction of Ferroptosis and cGAS-STING Activation by a H2S-Responsive Iridium(III) Complex for Cancer-Specific Therapy
Triggering ferroptosis represents a promising anticancer therapeutic strategy, but the
development of a selective ferroptosis inducer for cancer-specific therapy remains a great …
development of a selective ferroptosis inducer for cancer-specific therapy remains a great …
Design and synthesis of two iridium (Ⅲ) complex probes for rapid sensing of hydrogen sulfide
X Mu, W Zhang, MJ Li, F Fu - Sensors and Actuators B: Chemical, 2024 - Elsevier
Hydrogen sulfide (H 2 S) is an important sulfur-containing signaling molecule in the human
body, as well as a highly toxic gas that is soluble in water. A variety of pathological …
body, as well as a highly toxic gas that is soluble in water. A variety of pathological …
Mitochondria-targeted cyclometalated iridium (III) complex for H2S-responsive intracellular redox regulation as potent photo-oxidation anticancer agent
B Liu, X Huang, M Hu, Z Chen, W Zhang… - JBIC Journal of Biological …, 2022 - Springer
Owing to the safety and low toxicity, photodynamic therapy (PDT) for cancer treatment has
received extensive attention. However, the excess H2S in cancer cells reduces the PDT …
received extensive attention. However, the excess H2S in cancer cells reduces the PDT …
Recent advances in luminescent lanthanides and transition metal complex-based probes for imaging reactive oxygen, nitrogen, and sulfur species in living cells
R Sivakumar, NY Lee - Coordination Chemistry Reviews, 2024 - Elsevier
Reactive oxygen, nitrogen, and sulfur species (RONSS) regulate several pathological
activities in biological systems. These RONSS can be seriously harmful to the human body …
activities in biological systems. These RONSS can be seriously harmful to the human body …
Fluorescent probes for detecting and imaging mitochondrial hydrogen sulfide
YW Zhu, EE Ngowi, AQ Tang, T Chu, Y Wang… - Chemico-Biological …, 2025 - Elsevier
Hydrogen sulfide (H 2 S) is a potent redox-active signaling molecule commonly
dysregulated in disease states. The production of H 2 S and its involvement in various …
dysregulated in disease states. The production of H 2 S and its involvement in various …
Inducing and monitoring mitochondrial pH changes with an iridium (iii) complex via two-photon lifetime imaging
M Hu, XL Zhou, TX **ao, L Hao, Y Li - Dalton Transactions, 2023 - pubs.rsc.org
Real-time monitoring of mitochondrial dynamic changes plays a key role in the development
of mitochondria-targeted anticancer theranostic agents. In this work, a pH-responsive and …
of mitochondria-targeted anticancer theranostic agents. In this work, a pH-responsive and …
Four cyclometalated Ir (iii) complexes and insights into their luminescence, cytotoxicity and DNA/BSA binding performance
Q Yu, S Gu, X Yang, Q Jiang, P Shi - RSC advances, 2024 - pubs.rsc.org
Four cyclometalated Ir (III) complexes based on 4′-pN, N-bis (2-hydroxyethyl) benzyl-2,
2′: 6′, 2′′-terpyridine (TPYOH) and 4′-pN, N-bis (2-hydroxyethyl) benzyl-6′-benzyl …
2′: 6′, 2′′-terpyridine (TPYOH) and 4′-pN, N-bis (2-hydroxyethyl) benzyl-6′-benzyl …