SPECT has traditionally been regarded as nonquantitative. Advances in multimodality γ-
cameras (SPECT/CT), algorithms for image reconstruction, and sophisticated compensation …

The potential of targeted therapy with radiolabeled peptides has been reported in several
clinical trials. Although there have been many improvements in dose estimation, a general …

In internal radionuclide therapy, a growing interest in voxel-level estimates of tissue-
absorbed dose has been driven by the desire to report radiobiologic quantities that account …

Compared with conventional, whole-organ, S-factor-based dosimetry, 3-dimensional (3D),
patient-specific dosimetry better accounts for radionuclide distribution and anatomic patient …

Absolute quantification of radiotracer distribution using SPECT/CT imaging is of great
importance for dosimetry aimed at personalized radionuclide precision treatment. However …

Purpose In recent years, targeted radionuclide therapy with [177 Lu-DOTA 0, Tyr 3]
octreotate for neuroendocrine tumours has yielded promising results. This therapy may be …

Tumor dosimetry was performed for 177Lu-DOTATATE with the aims of better understanding
the range and variation of the tumor-absorbed doses (ADs), how different dosimetric …

Targeted radionuclide therapy (TRT) is a promising technique for cancer therapy. However,
in order to deliver the required dose to the tumor, minimize potential toxicity in normal …

The increasing availability of SPECT/CT devices with advanced technology offers the
opportunity for the accurate assessment of the radiation dose to the biological target volume …

Patients undergoing nuclear medicine procedures for cancer therapy are administered
radiopharmaceuticals that emit various types of radiation. Because radiation has differential …