Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to
elevated pressures within the pulmonary arteries. Five main groups of pulmonary …

ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …

Autoantibodies are frequently observed in healthy individuals. In a minority of these
individuals, they lead to manifestation of autoimmune diseases, such as rheumatoid arthritis …

Perivascular inflammation is a prominent pathologic feature in most animal models of
pulmonary hypertension (PH) as well as in pulmonary arterial hypertension (PAH) patients …

Pulmonary hypertension (PH) is a feature of a variety of diseases and continues to harbor
high morbidity and mortality. The main consequence of PH is right-sided heart failure which …

Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is an
acquired complex disease with patients suffering from the cardinal symptoms of fatigue, post …

Systemic sclerosis (SSc) is a multisystem autoimmune and vascular disease resulting in
fibrosis of various organs with unknown etiology. Accumulating evidence suggests that a …

Systemic sclerosis (SSc) is a chronic immune disorder of unknown origin, dominated by
excessive fibrosis responsible for cutaneous and pulmonary fibrosis, and by vascular …

Autoimmune rheumatic diseases are characterised by an abnormal immune system
response, complement activation, cytokines dysregulation and inflammation. In last years …

Pulmonary arterial hypertension (PAH), corresponding to group 1 of pulmonary
hypertension classification, is a rare disease with a major prognostic impact on morbidity …