Neuroinflammatory mechanisms in ischemic stroke: focus on cardioembolic stroke, background, and therapeutic approaches
One of the most important causes of neurological morbidity and mortality in the world is
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …
Inflammatory processes in cardiovascular disease: a route to targeted therapies
Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …
CD28− T cells: their role in the age-associated decline of immune function
The accumulation of CD28− T cells, particularly within the CD8 subset, is one of the most
prominent changes during T-cell homeostasis and function associated with aging in …
prominent changes during T-cell homeostasis and function associated with aging in …
Accelerated atherosclerosis in autoimmune rheumatic diseases
antibodies concomitant with larger atherosclerotic lesions that contained abundant CD4
cells. OxLDL is the type of LDL that is more likely to undergo uptake by macrophages, which …
cells. OxLDL is the type of LDL that is more likely to undergo uptake by macrophages, which …
Heat-shock proteins induce T-cell regulation of chronic inflammation
Immune responses to certain heat-shock proteins (HSPs) develop in almost all inflammatory
diseases; however, the significance of such responses is only now becoming clear. In …
diseases; however, the significance of such responses is only now becoming clear. In …
Pathogenesis of acute coronary syndromes
Experimental models of atherogenesis have provided a growing body of information about
molecular mechanisms of plaque growth; however, transition from coronary stability to …
molecular mechanisms of plaque growth; however, transition from coronary stability to …
Role of lymphocytes in myocardial injury, healing, and remodeling after myocardial infarction
U Hofmann, S Frantz - Circulation research, 2015 - Am Heart Assoc
A large body of evidence produced during decades of research indicates that myocardial
injury activates innate immunity. On the one hand, innate immunity both aggravates …
injury activates innate immunity. On the one hand, innate immunity both aggravates …
Innate immune signaling in cardiac ischemia
Despite advances in treatment of patients who suffer from ischemic heart disease, morbidity
related to myocardial infarction is increasing in Western societies. Acute and chronic …
related to myocardial infarction is increasing in Western societies. Acute and chronic …
Mechanisms of disease: atherosclerosis in autoimmune diseases
Y Sherer, Y Shoenfeld - Nature clinical practice Rheumatology, 2006 - nature.com
Atherosclerosis is a pathologic process affecting blood vessels, which leads to the
development of cardiovascular disease. The immune system is involved in atherogenesis …
development of cardiovascular disease. The immune system is involved in atherogenesis …
The influence of innate and adaptive immune responses on atherosclerosis
JL Witztum, AH Lichtman - Annual Review of Pathology …, 2014 - annualreviews.org
Both the chronic development of atherosclerotic lesions and the acute changes in lesion
phenotype that lead to clinical cardiovascular events are significantly influenced by the …
phenotype that lead to clinical cardiovascular events are significantly influenced by the …