Phase separation has long been observed within aqueous mixtures of two or more different
compounds, such as proteins, salts, polysaccharides and synthetic polymers. A growing …

In the current work, an experimental and theoretical study is performed on the urea-water
mixtures by using non-covalent interactions (NCI) and reduced density gradient (RDG) …

Superconcentrated aqueous electrolytes have shown promise as safe and high-voltage
lithium-ion battery (LIB) electrolytes. However, the interplay of lithium-ion solvation structure …

A study focused on the correlation among dielectric properties, molecular structure, and H-
bonding is presented using liquid formamides with increasing carbon chain lengths as a …

Despite being a simple and widely studied solution, a correlation between the structure and
dynamics of the hydrogen bond (HBond) network in alcohol-water binary mixtures remains …

While the liquid–liquid phase separation (LLPS) process in proteins has been studied in
great detail, it has not been widely explored how the associated protein hydration changes …

In this work, we investigated the influence of stabilizing (N, N, N-trimethylglycine) and
destabilizing (urea) osmolytes on the hydration spheres of biomacromolecules in folded …

A possible molecular origin of the contorting water-solubility of butanol isomers lies in the
self-association propensity of alcohols as well as on the specific interaction between the …

Density functional theory (DFT) calculations are performed to study the conformations,
hydrogen-bonding network, and the stabilities of all possible molecular associations, urea …

Trimethylamine N-oxide (TMAO) and urea are both osmolytes found in many marine
animals, yet they show opposite effects in (de-) stabilizing proteins. Gaining molecular-level …