Experimental evolution
Experimental evolution is the study of evolutionary processes occurring in experimental
populations in response to conditions imposed by the experimenter. This research approach …
populations in response to conditions imposed by the experimenter. This research approach …
The modern theory of biological evolution: an expanded synthesis
U Kutschera, KJ Niklas - Naturwissenschaften, 2004 - Springer
Abstract In 1858, two naturalists, Charles Darwin and Alfred Russel Wallace, independently
proposed natural selection as the basic mechanism responsible for the origin of new …
proposed natural selection as the basic mechanism responsible for the origin of new …
Antibiotic tolerance facilitates the evolution of resistance
Controlled experimental evolution during antibiotic treatment can help to explain the
processes leading to antibiotic resistance in bacteria. Recently, intermittent antibiotic …
processes leading to antibiotic resistance in bacteria. Recently, intermittent antibiotic …
Beneficial mutation–selection balance and the effect of linkage on positive selection
When beneficial mutations are rare, they accumulate by a series of selective sweeps. But
when they are common, many beneficial mutations will occur before any can fix, so there will …
when they are common, many beneficial mutations will occur before any can fix, so there will …
On the accumulation of deleterious mutations during range expansions
We investigate the effect of spatial range expansions on the evolution of fitness when
beneficial and deleterious mutations cosegregate. We perform individual‐based simulations …
beneficial and deleterious mutations cosegregate. We perform individual‐based simulations …
Antibiotic treatment enhances the genome-wide mutation rate of target cells
Although it is well known that microbial populations can respond adaptively to challenges
from antibiotics, empirical difficulties in distinguishing the roles of de novo mutation and …
from antibiotics, empirical difficulties in distinguishing the roles of de novo mutation and …
[HTML][HTML] Have you tried turning it off and on again? Oscillating selection to enhance fitness-landscape traversal in adaptive laboratory evolution experiments
Abstract Adaptive Laboratory Evolution (ALE) is a powerful tool for engineering and
understanding microbial physiology. ALE relies on the selection and enrichment of …
understanding microbial physiology. ALE relies on the selection and enrichment of …
The speed of evolution and maintenance of variation in asexual populations
Background The rate at which beneficial mutations accumulate determines how fast asexual
populations evolve, but this is only partially understood. Some recent clonal-interference …
populations evolve, but this is only partially understood. Some recent clonal-interference …
Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations
Laboratory experimental evolution provides a window into the details of the evolutionary
process. To investigate the consequences of long-term adaptation, we evolved 205 …
process. To investigate the consequences of long-term adaptation, we evolved 205 …
Expansion load and the evolutionary dynamics of a species range
Expanding populations incur a mutation burden, the so-called expansion load. Using a
mixture of individual-based simulations and analytical modeling, we study the expansion …
mixture of individual-based simulations and analytical modeling, we study the expansion …