Brain manganese and the balance between essential roles and neurotoxicity
Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …
organs, including the brain. Although its roles as a cofactor in several enzymes and in …
Manganese-induced parkinsonism and Parkinson's disease: shared and distinguishable features
Manganese (Mn) is an essential trace element necessary for physiological processes that
support development, growth and neuronal function. Secondary to elevated exposure or …
support development, growth and neuronal function. Secondary to elevated exposure or …
When pharmaceutical drugs become environmental pollutants: Potential neural effects and underlying mechanisms
Pharmaceutical drugs have become consumer products, with a daily use for some of them.
The volume of production and consumption of drugs is such that they have become …
The volume of production and consumption of drugs is such that they have become …
Air pollution exposure during pregnancy and childhood and brain morphology in preadolescents
MJ Lubczyńska, RL Muetzel, H El Marroun… - Environmental …, 2021 - Elsevier
Background Studies investigating the relationship between exposure to air pollution and
brain development using magnetic resonance images are emerging. However, most studies …
brain development using magnetic resonance images are emerging. However, most studies …
Manganese accumulation in the brain via various transporters and its neurotoxicity mechanisms
Manganese (Mn) is an essential trace element, serving as a cofactor for several key
enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and …
enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and …
Manganese exposure and neurocognitive outcomes in rural school-age children: the communities actively researching exposure study (Ohio, USA)
Background Manganese (Mn) plays a vital role in brain growth and development, yet
excessive exposure can result in neurotoxicity. Marietta, Ohio, is home to the nation's …
excessive exposure can result in neurotoxicity. Marietta, Ohio, is home to the nation's …
[HTML][HTML] The cGAS-STING-mediated NLRP3 inflammasome is involved in the neurotoxicity induced by manganese exposure
J Liu, X Zhang, H Wang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Heavy metal pollution has become a global health challenge. Exposure to heavy metals
represents a major health risk. Manganese (Mn) is an essential trace element but also an …
represents a major health risk. Manganese (Mn) is an essential trace element but also an …
[HTML][HTML] Associations of air pollution on the brain in children: a brain imaging study
M Guxens, MJ Lubczyńska… - … Health Effects Institute, 2022 - ncbi.nlm.nih.gov
BACKGROUND Although several epidemiological studies have assessed the association
between air pollution exposure during early life and child neurological development, it is yet …
between air pollution exposure during early life and child neurological development, it is yet …
Airborne manganese exposure and neurobehavior in school-aged children living near a ferro-manganese alloy plant
JLG Rodrigues, CFS Araújo, NR Dos Santos… - Environmental …, 2018 - Elsevier
Excessive exposure to Mn can lead to its accumulation in the brain with neurotoxic
consequences. In children, elevated Mn has been associated with deficits in certain …
consequences. In children, elevated Mn has been associated with deficits in certain …
[HTML][HTML] A breath of fresh air: Perspectives on inhaled nutrients and bacteria to improve human health
We propose that the human respiratory system and olfactory pathways sequester airborne
nutrients (vitamins, fatty acids and trace minerals) that are beneficial for health, which we …
nutrients (vitamins, fatty acids and trace minerals) that are beneficial for health, which we …