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The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function
JW Fawcett, T Oohashi, T Pizzorusso - Nature Reviews Neuroscience, 2019 - nature.com
Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …
Adolescence as a neurobiological critical period for the development of higher-order cognition
The transition from adolescence to adulthood is characterized by improvements in higher-
order cognitive abilities and corresponding refinements of the structure and function of the …
order cognitive abilities and corresponding refinements of the structure and function of the …
Hippocampal GABAergic inhibitory interneurons
KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …
of the total neuronal population; however, their remarkable anatomical and physiological …
Development and functions of the choroid plexus–cerebrospinal fluid system
The choroid plexus (ChP) is the principal source of cerebrospinal fluid (CSF), which has
accepted roles as a fluid cushion and a sink for nervous system waste in vertebrates …
accepted roles as a fluid cushion and a sink for nervous system waste in vertebrates …
Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2
Early life stress increases risk for depression. Here we establish a “two-hit” stress model in
mice wherein stress at a specific postnatal period increases susceptibility to adult social …
mice wherein stress at a specific postnatal period increases susceptibility to adult social …
Critical period regulation across multiple timescales
RK Reh, BG Dias, CA Nelson III, D Kaufer… - Proceedings of the …, 2020 - pnas.org
Brain plasticity is dynamically regulated across the life span, peaking during windows of
early life. Typically assessed in the physiological range of milliseconds (real time), these …
early life. Typically assessed in the physiological range of milliseconds (real time), these …
Critical periods in speech perception: new directions
A continuing debate in language acquisition research is whether there are critical periods
(CPs) in development during which the system is most responsive to environmental input …
(CPs) in development during which the system is most responsive to environmental input …
Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning
F Donato, SB Rompani, P Caroni - Nature, 2013 - nature.com
Learning and memory processes can be influenced by recent experience, but the
mechanisms involved are poorly understood. Enhanced plasticity during critical periods of …
mechanisms involved are poorly understood. Enhanced plasticity during critical periods of …
Balancing plasticity/stability across brain development
AE Takesian, TK Hensch - Progress in brain research, 2013 - Elsevier
The potency of the environment to shape brain function changes dramatically across the
lifespan. Neural circuits exhibit profound plasticity during early life and are later stabilized. A …
lifespan. Neural circuits exhibit profound plasticity during early life and are later stabilized. A …
[HTML][HTML] Development and plasticity of the primary visual cortex
JS Espinosa, MP Stryker - Neuron, 2012 - cell.com
Hubel and Wiesel began the modern study of development and plasticity of primary visual
cortex (V1), discovering response properties of cortical neurons that distinguished them from …
cortex (V1), discovering response properties of cortical neurons that distinguished them from …