The peroxisome proliferator activated receptor γ (PPARγ) is a nuclear receptor highly
expressed in the colon and playing a key role in bacterial induced inflammation. Regulation …

Recent studies on diseases which involve insulin insensitivity (eg obesity, type 2 diabetes
and atherosclerosis) also show increased cytokine production and markers of inflammation …

The cross-regulation of Wnt/β-catenin/Tcf ligands, kinases, and transcription factors with
members of the nuclear receptor (NR) family has emerged as a clinically and …

Background Type 2 diabetes mellitus (DM), characterized by peripheral insulin resistance, is
the most common form of diabetes. Probiotics are live micro-organisms that, when …

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that
mediate the effects of fatty acids and their derivatives at the transcriptional level. These …

Type 2 diabetes mellitus is characterised by insulin resistance as well as progressive
pancreatic β cell dysfunction. The cornerstone of current oral blood-glucose lowering …

Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of a class of
nuclear hormone receptors intimately involved in the regulation of expression of myriad …

Abstract α-Methylacyl-CoA racemase (AMACR) is a mitochondrial and peroxisomal enzyme
involved in the metabolism of branched-chain fatty acid and bile acid intermediates …

Rationale: The NF-E2 related factor 2 (Nrf2)–antioxidant response element (ARE) pathway
is essential for protection against oxidative injury and inflammation including hyperoxia …

Peroxisome proliferator-activated receptors (PPARα, PPARβ/δ and PPARγ) are a family of
nuclear receptors that are activated by binding of natural ligands, such as polyunsaturated …