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The regulation of hyphae growth in Candida albicans
In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …
threatening invasive infections with mortality rates approaching 40% despite treatment …
Growth of Candida albicans hyphae
PE Sudbery - Nature Reviews Microbiology, 2011 - nature.com
The fungus Candida albicans is often a benign member of the mucosal flora; however, it
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
Abstract Background The Critical Assessment of Functional Annotation (CAFA) is an
ongoing, global, community-driven effort to evaluate and improve the computational …
ongoing, global, community-driven effort to evaluate and improve the computational …
Mechanism of Candida pathogenesis: revisiting the vital drivers
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …
Candida albicans dimorphism as a therapeutic target
The ability to switch between yeast and hyphal growth forms (dimorphism) is one of the most
discussed and best investigated virulence attributes of the human pathogenic fungus …
discussed and best investigated virulence attributes of the human pathogenic fungus …
[HTML][HTML] Invasive candidiasis: update and current challenges in the management of this mycosis in South America
Invasive candidiasis encompassing Candida bloodstream infections and deep-seated
candidiasis can become a persistent health problem. These infections are caused by …
candidiasis can become a persistent health problem. These infections are caused by …
Mechanisms of fungal dissemination
AB Strickland, M Shi - Cellular and Molecular Life Sciences, 2021 - Springer
Fungal infections are an increasing threat to global public health. There are more than six
million fungal species worldwide, but less than 1% are known to infect humans. Most of …
million fungal species worldwide, but less than 1% are known to infect humans. Most of …
[HTML][HTML] Candida albicans interactions with epithelial cells and mucosal immunity
Candida albicans interactions with epithelial cells are critical for commensal growth, fungal
pathogenicity and host defence. This review will outline our current understanding of C …
pathogenicity and host defence. This review will outline our current understanding of C …
Candidalysin delivery to the invasion pocket is critical for host epithelial damage induced by Candida albicans
The human pathogenic fungus Candida albicans is a frequent cause of mucosal infections.
Although the ability to transition from the yeast to the hypha morphology is essential for …
Although the ability to transition from the yeast to the hypha morphology is essential for …
Candida survival strategies
Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …
and Candida parapsilosis, are successful colonizers of a human host. Under certain …