The early immune response to HIV-1 infection is likely to be an important factor in
determining the clinical course of disease. Recent data indicate that the HIV-1 quasispecies …

Dendritic cells (DCs) are crucial for the generation and the regulation of adaptive immunity.
Because DCs have a pivotal role in marshalling immune responses, HIV has evolved ways …

Although vaccines have been highly successful in preventing and treating many infectious
diseases (including smallpox, polio and diphtheria) diseases prevalent in the develo** …

The balance between proinflammatory mechanisms and the dampening of excessive
immune activation is critical for successful clearance of a pathogen without harm to the host …

Oropharyngeal and esophageal candidiases remain significant causes of morbidity in
human immunodeficiency virus (HIV)-infected patients, despite the dramatic ability of …

Human immunodeficiency virus type 1 (HIV-1) infection of dendritic cells (DCs) plays an
important role in HIV-1 transmission and pathogenesis. Here, we studied the susceptibility of …

Identification of cellular factors involved in HIV-1 entry and transmission at mucosal surfaces
is critical for understanding viral pathogenesis and development of effective prevention …

Myeloid and plasmacytoid dendritic cells (DCs) are important mediators of both innate and
adaptive immunity against pathogens such as HIV. During the course of HIV infection, blood …

The C-type lectin dendritic cell-specific ICAM 3-grabbing nonintegrin (DC-SIGN)/CD209
efficiently binds several pathogens, including HIV-1. DC-SIGN is expressed on monocyte …

Abstract DC-SIGN, a C-type lectin expressed on dendritic cells (DCs), can sequester human
immunodeficiency virus (HIV) virions in multivesicular bodies. Here, using large-scale gene …