Protozoan parasites have developed elaborate motility systems that facilitate infection and
dissemination. For example, amoebae use actin-rich membrane extensions called …

Toxoplasma gondii is an obligate intracellular pathogen within the phylum Apicomplexa.
This protozoan parasite is one of the most widespread, with a broad host range including …

The Apicomplexa are a phylum of diverse obligate intracellular parasites including
Plasmodium spp., the cause of malaria; Toxoplasma gondii and Cryptosporidium parvum …

Toxoplasmosis is the clinical and pathological consequence of acute infection with the
obligate intracellular apicomplexan parasite Toxoplasma gondii. Symptoms result from …

Obligate intracellular apicomplexan parasites rely on gliding motion powered by their
actomyosin system to disperse throughout tissues and to penetrate host cells. Toxoplasma …

Apicomplexan parasites, including Toxoplasma gondii and Plasmodium sp., are obligate
intracellular protozoa. They enter into a host cell by attaching to and then creating an …

Intracellular parasites use various strategies to invade cells and to subvert cellular signaling
pathways and, thus, to gain a foothold against host defenses. Efficient cell entry, ability to …

Plasmodium sporozoite invasion of liver cells has been an extremely elusive event to study.
In the prevailing model, sporozoites enter the liver by passing through Kupffer cells, but this …

Calcium-regulated exocytosis is a ubiquitous process in eukaryotes, whereby secretory
vesicles fuse with the plasma membrane and release their contents in response to an …

The phylum Apicomplexa comprises important eukaryotic parasites that invade host tissues
and cells using a unique mechanism of gliding motility. Gliding is powered by actomyosin …