Differences in beta-lactam and penicillin allergy: beyond the West and focusing on Asia-Pacific

HWF Mak, MHY Yeung, JCY Wong, V Chiang… - Frontiers in …, 2022 - frontiersin.org
Beta-lactam (BL) antibiotic “allergy” labels are common, but often overdiagnosed. Although
much research has been focused on the BL allergy and the delabelling process in the West …

Updates in SJS/TEN: collaboration, innovation, and community

ME Marks, RK Botta, R Abe, TM Beachkofsky… - Frontiers in …, 2023 - frontiersin.org
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN) is a predominantly drug-
induced disease, with a mortality rate of 15–20%, that engages the expertise of multiple …

Prospective, multicenter, head-to-head comparison between allergists versus nonallergists in low-risk penicillin allergy delabeling: effectiveness, safety, and quality of …

JCY Wong, AKC Kan, TSH Chik, MY Chu… - The Journal of Allergy …, 2024 - Elsevier
Background Penicillin “allergy” labels are prevalent but frequently misdiagnosed.
Mislabelled allergies are associated with adverse outcomes and increased antimicrobial …

Identifying the most at-risk age-group and longitudinal trends of drug allergy labeling amongst 7.3 million individuals in Hong Kong

V Chiang, AKC Kan, C Saha, EYL Au, PH Li - BMC medicine, 2024 - Springer
Background Incorrect drug 'allergy'labels remain a global public health concern. Identifying
regional trends of drug allergy labeling can guide appropriate public health interventions …

APAAACI clinical pathway on direct provocation testing for penicillin allergy delabeling

PH Li, BYH Thong, R Pawankar… - Asia Pacific …, 2023 - journals.lww.com
Background: Allergy to penicillin is commonly reported in many countries and is an
overwhelming global public health concern. Penicillin allergy labels can lead to the use of …

Impact of a drug allergy education course for non‐specialists: Findings from ADAPT—A randomized crossover trial

M Lucas, HWF Mak, JTY Lee, R Kulkarni, SSC Chan… - Allergy, 2024 - Wiley Online Library
Background The consequences of drug allergy remain a global health concern. Drug allergy
is often a neglected topic and many non‐specialists lack sufficient knowledge or confidence …

NSAID hypersensitivity in the pediatric population: classification and diagnostic strategies

O Cavkaytar, M Arga - Journal of Asthma and Allergy, 2022 - Taylor & Francis
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most frequently
administered drugs, mainly for their anti-pyretic, but also for pain-relieving and anti …

Prevalence and impact of misdiagnosed drug allergy labels among patients with hereditary angioedema

JCY Wong, N Cheong, CS Lau, PH Li - Frontiers in Allergy, 2022 - frontiersin.org
Introduction Hereditary angioedema (HAE) is a rare condition with presents with episodic
attacks of angioedema, which is often misdiagnosed as allergy, and associated with …

[HTML][HTML] Fatal events associated with adverse drug reactions in the Korean national pharmacovigilance database

HG Jo, K Jeong, JY Ryu, S Park, YS Choi… - Journal of Personalized …, 2021 - mdpi.com
Adverse drug reactions (ADRs) pose a global public health threat, substantially contributing
to death. Due to the relative paucity of clinical evidence regarding fatal ADRs, this study was …

Piperacillin-tazobactam allergies: an exception to usual penicillin allergy

JCY Wong, EYL Au, HHF Yeung… - Allergy, Asthma & …, 2020 - pmc.ncbi.nlm.nih.gov
Purpose The majority of penicillin allergy labels are false, and skin tests (ST) have high
negative predictive value (NPV) of up to 90%. Piperacillin-tazobactam (PT) allergy has been …