Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

Clinical studies suggest that diets rich in ω-3 polyunsaturated fatty acids (PUFAs) provide
beneficial anti-inflammatory effects, in part through their conversion to bioactive metabolites …

Cannabinoid receptor activation is involved in homeostatic regulation of the body. These
receptors are activated by cannabinoids, that include the active constituents of Cannabis …

Notwithstanding the ongoing debate on their full potential in health and disease, there is
general consensus that n-3 PUFAs play important physiological roles. Increasing dietary n-3 …

Cardiovascular diseases are one of the leading causes of mortality in developed countries.
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …

Background Neuroinflammatory processes are considered a double-edged sword, having
both protective and detrimental effects in the brain. Microglia, the brain's resident innate …

Docosahexaenoic acid (DHA) is an essential fatty acid that is recognized as a beneficial
dietary constituent and as a source of the anti-inflammatory specialized proresolving …

N-Docosahexaenoylethanolamine (synaptamide) is an endocannabinoid-like metabolite
endogenously synthesized from docosahexaenoic acid (DHA, 22: 6n-3), the major omega-3 …

Nile tilapia Oreochromis niloticus is a freshwater fish but can tolerate a wide range of
salinities. The mechanism of salinity adaptation at the molecular level was studied using …