Cellular and molecular mechanisms in the hypoxic tissue: role of HIF‐1 and ROS
Reactive oxygen species such as superoxide anion radicals (O2−) and hydrogen peroxide
(H2O2) have for long time been recognized as undesirable by‐products of the oxidative …
(H2O2) have for long time been recognized as undesirable by‐products of the oxidative …
Pharmacological models and approaches for pathophysiological conditions associated with hypoxia and oxidative stress
Hypoxia is the failure of oxygenation at the tissue level, where the reduced oxygen delivered
is not enough to satisfy tissue demands. Metabolic depression is the physiological …
is not enough to satisfy tissue demands. Metabolic depression is the physiological …
Hemoglobin changes after long-term intermittent work at high altitude
Chronic high altitude hypoxia leads to an increase in red cell numbers and hemoglobin
concentration. However, the effects of long-term intermittent hypoxia on hemoglobin …
concentration. However, the effects of long-term intermittent hypoxia on hemoglobin …
[LIVRE][B] Ward, milledge and west's high altitude medicine and physiology
AM Luks, PN Ainslie, JS Lawley, RC Roach… - 2021 - taylorfrancis.com
This pre-eminent work has developed over six editions in response to man's attempts to
climb higher and higher unaided, and to spend more time at altitude for both work and …
climb higher and higher unaided, and to spend more time at altitude for both work and …
Long-term chronic intermittent hypoxia: a particular form of chronic high-altitude pulmonary hypertension
J Brito, P Siques, E Pena - Pulmonary Circulation, 2020 - journals.sagepub.com
In some subjects, high-altitude hypobaric hypoxia leads to high-altitude pulmonary
hypertension. The threshold for the diagnosis of high-altitude pulmonary hypertension is a …
hypertension. The threshold for the diagnosis of high-altitude pulmonary hypertension is a …
Mechanisms of cardiovascular protection associated with intermittent hypobaric hypoxia exposure in a rat model: role of oxidative stress
More than 140 million people live and works (in a chronic or intermittent form) above 2500 m
worldwide and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated …
worldwide and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated …
A study of survival strategies for improving acclimatization of lowlanders at high-altitude
P Sharma, S Mohanty, Y Ahmad - Heliyon, 2023 - cell.com
Human Acclimatization and therapeutic approaches are the core components for
conquering the physiological variations at high altitude (≥ 2500 m) exposure. The declined …
conquering the physiological variations at high altitude (≥ 2500 m) exposure. The declined …
Effects of zinc on the right cardiovascular circuit in long-term hypobaric hypoxia in wistar rats
K Arriaza, J Brito, P Siques, K Flores… - International journal of …, 2023 - mdpi.com
Hypobaric hypoxia under chromic conditions triggers hypoxic pulmonary vasoconstriction
(HPV) and right ventricular hypertrophy (RVH). The role of zinc (Zn) under hypoxia is …
(HPV) and right ventricular hypertrophy (RVH). The role of zinc (Zn) under hypoxia is …
Work at high altitude and non-fatal cardiovascular disease associated with unfitness to work: Prospective cohort observation
Introduction Mining at high altitude exposes workers to hypoxic environment and cold
climate in addition to conventional hazards in mining, but very little is known on how to …
climate in addition to conventional hazards in mining, but very little is known on how to …
Biomechanical and structural responses of the aorta to intermittent hypobaric hypoxia in a rat model
A Utrera, Á Navarrete, A González-Candia… - Scientific Reports, 2022 - nature.com
High altitude hypoxia is a condition experienced by diverse populations worldwide. In
addition, several jobs require working shifts where workers are exposed to repetitive cycles …
addition, several jobs require working shifts where workers are exposed to repetitive cycles …