Multiple sclerosis: current and emerging disease-modifying therapies and treatment strategies

DM Wingerchuk, JL Carter - Mayo Clinic Proceedings, 2014 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating central nervous system
disease that typically strikes young adults, especially women. The pathobiology of MS …

Pregnancy-related issues in women with multiple sclerosis: an evidence-based review with practical recommendations

B Canibaño, D Deleu, B Mesraoua… - Journal of drug …, 2020 - Taylor & Francis
Objective To review the current evidence regarding pregnancy-related issues in multiple
sclerosis (MS) and to provide recommendations specific for each of them. Research design …

[HTML][HTML] Pregnancy and multiple sclerosis: an update

G Varytė, A Arlauskienė… - Current Opinion in …, 2021 - journals.lww.com
Pregnancy and multiple sclerosis: an update : Current Opinion in Obstetrics and Gynecology
Pregnancy and multiple sclerosis: an update : Current Opinion in Obstetrics and Gynecology …

Influence of pregnancy in multiple sclerosis and impact of disease-modifying therapies

IL Simone, C Tortorella, A Ghirelli - Frontiers in Neurology, 2021 - frontiersin.org
Purpose of this Review: This article is a systematic review on the influence pregnancy has
on multiple sclerosis and the resulting impact of disease-modifying therapies. Findings …

An updated review of teriflunomide's use in multiple sclerosis

AE Miller - Neurodegenerative disease management, 2021 - Taylor & Francis
Teriflunomide, a once daily, oral disease-modifying therapy, has demonstrated consistent
efficacy, safety and tolerability in patients with relapsing forms of multiple sclerosis (MS) and …

From leflunomide to teriflunomide: drug development and immunosuppressive oral drugs in the treatment of multiple sclerosis

L Aly, B Hemmer, T Korn - Current Neuropharmacology, 2017 - ingentaconnect.com
Background: Immunosuppressive drugs have been used in the treatment of multiple
sclerosis (MS) for a long time. Today, orally available second generation …

How to switch disease-modifying treatments in multiple sclerosis: guidelines from the French Multiple Sclerosis Society (SFSEP)

K Bigaut, M Cohen, F Durand-Dubief, E Maillart… - Multiple Sclerosis and …, 2021 - Elsevier
Background Today, there are no recommendations on switching disease-modifying
treatments (DMTs) in multiple sclerosis (MS). Objectives To establish guidelines on …

Featured Article: Teriflunomide, an immunomodulatory drug, exerts anticancer activity in triple negative breast cancer cells

O Huang, W Zhang, Q Zhi, X Xue… - Experimental …, 2015 - journals.sagepub.com
Triple-negative breast cancer (TNBC) is defined as a group of primary breast cancers
lacking expression of estrogen, progesterone, and human epidermal growth factor receptor …

Teriflunomide (Aubagio®) for the treatment of multiple sclerosis

A Bar-Or - Experimental neurology, 2014 - Elsevier
Teriflunomide (Aubagio®) is a once-daily oral immunomodulatory disease modifying
therapy (DMT) presently approved in several regions, including Europe, North America …

Saliva as blood alternative in therapeutic monitoring of teriflunomide—development and validation of the novel analytical method

B Sankowski, S Michorowska, E Raćkowska… - International Journal of …, 2022 - mdpi.com
Therapeutic drug monitoring (TDM) is extremely helpful in individualizing dosage regimen of
drugs with narrow therapeutic ranges. It may also be beneficial in the case of drugs …