The Light-Oxygen-Voltage domain family of proteins is widespread in biology where they
impart sensory responses to signal transduction domains. The small, light responsive LOV …

Photoreceptor flavoproteins of the LOV, BLUF, and cryptochrome families are ubiquitous
among the three domains of life and are configured as UVA/blue-light systems not only in …

The light-oxygen-voltage (LOV) domains of phototropins emerged as essential constituents
of light-sensitive proteins, hel** initiate blue light-triggered responses. Moreover, these …

Background: Visible light is absorbed by photoacceptors in pigmented and non-pigmented
mammalian cells, activating signaling cascades and downstream mechanisms that lead to …

The mechanism of light-triggered conformational change and signaling in light-oxygen-
voltage (LOV) domains remains elusive in spite of extensive investigation and their use in …

The ability to manipulate expression of exogenous genes in particular regions of living
organisms has profoundly transformed the way we study biomolecular processes involved in …

Optogenetics has been, and will continue to be, a boon to mechanistic studies of cellular
processes. Genetically encodable proteins that sensitize the production of reactive oxygen …

Algae, plants, bacteria and fungi contain Light-Oxygen-Voltage (LOV) domains that function
as blue light sensors to control cellular responses to light. All LOV domains contain a bound …

Phototropins are one of several classes of photoreceptors used by plants and algae to
respond to light. These proteins contain flavin-binding LOV (Light-Oxygen-Voltage) domains …

Migrating birds fly thousands of miles or more, often without visual cues and in treacherous
winds, yet keep direction. They employ for this purpose, apparently as a powerful …