The extracellular matrix (ECM) is an important component of the tumor microenvironment
(TME), having several important roles related to the hallmarks of cancer. In cancer, multiple …

During tumor development, tumor cells constantly communicate with the surrounding
microenvironment through both biochemical and biophysical cues. In particular, the tumor …

Prostate cancer is a main urological disease associated with significant morbidity and
mortality. Radical prostatectomy and radiotherapy are potentially curative for localized …

Transforming growth factor-β (TGF-β) promotes tumor invasion and metastasis by inducing
epithelial-mesenchymal transition (EMT). EMT is often related with acquisition of stemness …

In a previous study, we found that microRNA (miRNA)-200a suppresses Wnt/β-catenin
signaling by interacting with β-catenin, thereby inhibiting migration, invasion and …

Benign prostate hyperplasia (BPH) is a major cause of lower urinary tract symptoms, with an
increased volume of transitional zone and associated with increased stromal cells. It is …

Transforming growth factor β (TGF‐β) is part of the transforming growth factor β superfamily
which is involved in many physiological processes and closely related to the …

The 5-year survival rate for colorectal cancer is approximately 55% because of its invasion
and metastasis. The epithelial–mesenchymal transition (EMT) is one of the well-defined …

The Nectin cell adhesion molecule (Nectin) family members are Ca 2+‑independent
immunoglobulin‑like cellular adhesion molecules (including Nectins 1‑4), involved in cell …

miRNA regulate gene expression at post-transcriptional level and fine-tune the key
biological processes, including cancer progression. Here, we demonstrate the involvement …