Interest in neurofilaments has risen sharply in recent years with recognition of their potential
as biomarkers of brain injury or neurodegeneration in CSF and blood. This is in the context …

Traumatic brain injury (TBI) is one of the world's leading causes of morbidity and mortality
among young individuals. TBI applies powerful rotational and translational forces to the …

Axonal degeneration is responsible for disease progression and accumulation of disability
in many neurodegenerative conditions. The axonal degenerative process can generate a …

Traditionally, researchers have believed that axons are highly dependent on their cell
bodies for long-term survival. However, recent studies point to the existence of axon …

Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …

Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …

Background Axonal damage and loss substantially contribute to the incremental
accumulation of clinical disability in progressive multiple sclerosis. Here, we assessed the …

Abstract Since Waller and Cajal in the nineteenth and early twentieth centuries, laboratory
traumatic peripheral nerve injury studies have provided great insight into cellular and …

Current therapies for nerve regeneration within injured tissues have had limited success due
to complicated neural anatomy and inhibitory barriers in situ. Recent advancements in 3D …

Axonal injury and degeneration, whether primary or secondary, contribute to the morbidity
and mortality seen in many acquired and inherited central nervous system (CNS) and …